Patent
Intravascular devices and fibrosis-inducing agents
William L. Hunter,David M. Gravett,Philip M. Toleikis,Arpita Maiti,Pierre E. Signore,Richard T. Liggins,Dechi Guan +6 more
TLDR
In this article, compositions and methods for use in the treatment of aneurysms and unstable arterial (vulnerable) plaque are described and compared for use with fibrosing agents.Abstract:
Intravascular devices (e.g., stents, stent grafts, covered stents, aneurysm coils, embolic agents and drug delivery catheters and balloons) are used in combination with fibrosing agents in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or to promote fibrosis betweent the devices and the host tissues. Compositions and methods are described for use in the treatment of aneurysms and unstable arterial (vulnerable) plaque.read more
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Patent
Coated implantable medical device
TL;DR: A coated implantable medical device as discussed by the authors includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract.
Patent
Methods and apparatus for thermally-induced renal neuromodulation
TL;DR: In this article, thermally-induced renal neuromodulation is achieved via delivery of a pulsed thermal therapy, where the parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors.
Patent
Tuned rf energy and electrical tissue characterization for selective treatment of target tissues
Corbett W. Stone,Michael F. Hoey,Tom A. Steinke,Raphael M. Michel,Arthur G. Blanck,Marlene Kay Truesdale,Bret Herscher +6 more
TL;DR: A catheter and catheter system can use energy tailored for remodeling and/or removal of target material along a body lumen, often of atherosclerotic material of a blood vessel of a patient as discussed by the authors.
Patent
Selectable Eccentric Remodeling and/or Ablation of Atherosclerotic Material
TL;DR: In this paper, a catheter and catheter system for eccentric remodeling and/or removal of atherosclerotic material of a blood vessel of a patient include an elongate flexible catheter body with a radially expandable structure.
Patent
Methods and apparatus for performing a non-continuous circumferential treatment to a body lumen
Denise Demarais,Hanson S. Gifford,Nicolas Zadno,Mark Deem,Benjamin J. Clark,Andrew Wu,Kenneth J. Michlitsch +6 more
TL;DR: In this article, a non-continuous circumferential treatment of a body lumen is described, where an apparatus is used to deliver energy at a first lengthwise and angular position within the lumen to create a less-than-full treatment zone at the first position.
References
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Patent
Anti-angiogenic compositions and methods of use
TL;DR: In this article, an anti-angiogenic factor and a polymeric carrier were used for embolization of blood vessels and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
Patent
Therapeutic inhibitor of vascular smooth muscle cells
TL;DR: In this paper, the authors present methods for the direct and/or targeted delivery of therapeutic agents to vascular smooth muscle cells that cause a dilation and fixation of the vascular lumen by inhibiting smooth muscle cell contraction, thereby constituting a biological stent.
Patent
Biodegradable drug delivery vascular stent
TL;DR: A stent is a main body of a generally tubular shape for insertion into a lumen of a vessel of a living being as mentioned in this paper, which includes a substantially biodegradable matrix having collagen IV and laminin that encloses voids within the matrix.
Patent
Bifurcated endoluminal prosthesis
TL;DR: An introduction for delivering into the vasculature a straight or bifurcated stent or prosthesis is given in this paper, where the stents also include barbs, fabric covering and radiopaque markers.