Open AccessJournal Article
Isolation of a novel bioactive compound from Rhizophora mucronata for Methicillin Resistant Staphylococcus aureus (MRSA) and compound toxicity assessment in Zebra fish embryos.
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TLDR
Bioactive compound from methanolic extract of Rhizophora mucronata showed antagonistic activity against Staphylococcus aureus (MRSA) and the effect of the compound toxicity was analyzed and studied in Zebra fish embryos.About:
This article is published in Journal of Pharmacy Research.The article was published on 2010-01-01 and is currently open access. It has received 7 citations till now. The article focuses on the topics: Methicillin Susceptible Staphylococcus Aureus & Minimum inhibitory concentration.read more
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Can Scientific Evidence Support Using Bangladeshi Traditional Medicinal Plants in the Treatment of Diarrhoea? A Review on Seven Plants
TL;DR: There is limited scientific evidence supporting the traditional use of these plants against diarrhoea, but most promising are the barks from D. peregrina, X. granatum and X. moluccensis which contain tannins and have shown promising results in antidiarrhoeal mice models.
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Antimicrobial silver nanoparticle induces organ deformities in the developing Zebrafish (Danio rerio) embryos
Rajaretinam Rajesh Kannan,Arockya Jeyabalan Avila Jerley,Muthiah Ranjani,Vincent Samuel Gnana Prakash +3 more
TL;DR: Results shows silver nanoparticles dis-rupts the normal organogenesis during development and further detailed studies are needed to prove silver nanopartcles are an antimicrobial agent for use in humans.
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Cynodon dactylon and Sida acuta extracts impact on the function of the cardiovascular system in zebrafish embryos
TL;DR: An assay that can measure changes in cardiac function in response to herbal small molecules and determine the cardiogenic effects by microvideography is developed.
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Isolation of a small molecule with anti-MRSA activity from a mangrove symbiont Streptomyces sp. PVRK-1 and its biomedical studies in Zebrafish embryos
TL;DR: The aim of the present study was to isolate the anti-MRSA molecule from the Mangrove symbiont Streptomyces and its biomedical studies in Zebrafish embryos and assessed that the molecule was non toxic at the minimal inhibitory concentration of MRSA.
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Efficacy of Plectranthus amboinicus (Lour.) Spreng in a Murine Model of Methicillin-Resistant Staphylococcus aureus Skin Abscesses
Francisco Fábio Martins de Oliveira,Alba Fabíola Costa Torres,Thially Braga Gonçalves,Gilvandete M. P. Santiago,Cibele Barreto Mano de Carvalho,Milena Braga Aguiar,Lilia Maria Carneiro Camara,Silvia Helena Rabenhorst,Alice Maria Costa Martins,José Telmo Valença Junior,Aparecida Tiemi Nagao-Dias +10 more
TL;DR: The present study proved the effectiveness of P. amboinicus fractions against MRSA using in vitro and in vivo assays, and found them effective in treating the animals in a dose-dependent fashion.
References
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Indian Medicinal Plants
TL;DR: Indian medicinal plants/, Indian medicinal plants /, مرکز فناوری اطلاعات و اصاع رسانی, کδاوρزی
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Zebrafish as a model vertebrate for investigating chemical toxicity.
TL;DR: An overview of the rapidly increasing use of zebrafish in toxicology is presented, both in identifying endpoints of toxicity and in elucidating mechanisms of toxicity.
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Sensitivity of zebrafish to environmental toxins implicated in Parkinson's disease
TL;DR: It is reported that adult zebrafish display behavioral alterations, including decreased locomotor activity in response to MPTP, whereas larvalZebrafish exhibited developmental, behavioral, and DA sensitivity to these agents, suggesting that zebra fish could be a valuable model for genetically dissecting the molecular mechanisms underlying the neurotoxicity of PD-inducing agents.
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Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery.
TL;DR: The zebrafish is emerging as a versatile in vivo animal model to identify off‐target effects that need investigation and further clarification early in the drug discovery process to reduce the current, high degree of attrition in development.
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Antibacterial activity of psidium guajava linn. stem bark extracts on multi drug resistant (mdr) community acquired methicillin-resistant staphylococcus aureus (ca-mrsa)
Chibuike Ibe,Ngozi Lucy Maduagwu +1 more