July 2017 at a glance: clinical assessment, biomarkers, cardiac imaging and treatment.
Reads0
Chats0
TLDR
Both baseline BP and long-term BP changes had independent prognostic value and the patients with the stable BP values during follow-up had the best prognosis.Abstract:
While the relation between absolute blood pressure (BP) and outcomes in patients with heart failure (HF) is relatively well established,1,2 the prognostic significance of long-term BP changes has been assessed only in retrospective analyses of randomized clinical trials.3 The prognostic significance of long-term BP changes was assessed by Schmid et al. in a retrospective analysis of 927 HF patients followed at their centre for a median of 7.7 years.4 There were 220 deaths and 70 patients undergoing heart transplantation. Both baseline BP and long-term BP changes had independent prognostic value. The patients with the stable BP values during follow-up had the best prognosis. Either an increase or a decrease > ±10 mmHg per year was associated with reduced survival with hazard ratios of 1.8 and 2.0, respectively.4read more
References
More filters
Journal ArticleDOI
Organ dysfunction, injury and failure in acute heart failure: from pathophysiology to diagnosis and management. A review on behalf of the Acute Heart Failure Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC).
Veli-Pekka Harjola,Wilfried Mullens,Marek Banaszewski,Johann Bauersachs,Hans-Peter Brunner-La Rocca,Ovidiu Chioncel,Sean P. Collins,Wolfram Doehner,Gerasimos Filippatos,Andreas J. Flammer,Valentin Fuhrmann,Mitja Lainscak,Johan Lassus,Matthieu Legrand,Josep Masip,Christian Mueller,Zoltán Papp,John Parissis,Elke Platz,Alain Rudiger,Frank Ruschitzka,Andreas Schaefer,Petar M. Seferovic,Hadi Skouri,Mehmet Yilmaz,Alexandre Mebazaa +25 more
TL;DR: The prevention and correction of organ dysfunction represent a therapeutic target of interest in AHF and should be evaluated in clinical trials to determine if such interventions impact mortality, morbidity and patient‐centred outcomes.
Journal ArticleDOI
Left ventricular assist device therapy in advanced heart failure: patient selection and outcomes.
Finn Gustafsson,Joseph G. Rogers +1 more
TL;DR: Outcome after LVAD implantation in stable patients is superior to that of ‘crash and burn’ patients or patients sliding on inotropes, favouring early referral and implantation, and current outcomes clearly justify use of LVADs in advanced HF.
Journal ArticleDOI
Different correlates but similar prognostic implications for right ventricular dysfunction in heart failure patients with reduced or preserved ejection fraction
Stefano Ghio,Marco Guazzi,Angela Beatrice Scardovi,Catherine Klersy,Francesco Clemenza,Erberto Carluccio,Pier Luigi Temporelli,Andrea Rossi,Pompilio Faggiano,Egidio Traversi,Olga Vriz,Frank Lloyd Dini +11 more
TL;DR: To evaluate whether the clinical and echocardiographic correlates and the prognostic significance of right ventricular (RV) dysfunction are different in heart failure patients with reduced (HFrEF), mid‐range (HFmrEF), or preserved (HFpEF) left ventricular ejection fraction, a large number of patients with HFrEF, mid-range, or preserved patients are surveyed.
Journal ArticleDOI
Right ventricular dysfunction in heart failure with preserved ejection fraction: a systematic review and meta-analysis
Thomas M. Gorter,Elke S. Hoendermis,Dirk J. van Veldhuisen,Adriaan A. Voors,Carolyn S.P. Lam,Bastiaan Geelhoed,Tineke P. Willems,Joost P. van Melle +7 more
TL;DR: A systematic review and meta‐analysis according to Preferred Reporting Items for Systematic Reviews and Meta‐Analyses on the prevalence and prognostic value of RV dysfunction in heart failure with preserved ejection fraction is conducted.
Journal ArticleDOI
Prediction of right ventricular failure after ventricular assist device implant: systematic review and meta-analysis of observational studies
Diego Bellavia,Attilio Iacovoni,Cesare Scardulla,Lorenzo Moja,Michele Pilato,Sudhir S. Kushwaha,Michele Senni,Francesco Clemenza,Valentina Agnese,Calogero Falletta,Giuseppe Romano,Joseph F. Maalouf,Michael Dandel +12 more
TL;DR: A systematic review and meta‐analysis of observational studies of risk factors associated with RVF after LVAD implant found that patients on ventilatory support or CRRT are at high risk for post‐LVAD RVF, similarly to patients with slightly increased INR, high NT‐proBNP or leukocytosis.