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Journal ArticleDOI

Kokusaginine: Plant sources and its isolation fromPtelea trifoliata root bark

R. K. Mulvey, +1 more
- 01 Jan 1969 - 
- Vol. 23, Iss: 1, pp 75-81
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TLDR
The incorporation of 2% hydrochloric acid solution and hot benzene in the extraction procedure appeared to facilitate the isolation of kokusaginine as discussed by the authors, and an Rf value of 0.70 has been determined for the alkaloid.
Abstract
1. Kokusaginine, as the free base, has been isolated in a yield of 0.015% from root bark ofPtelea trifoliata. 2. By descending paper partition chromatography an Rf value of 0.70 has been determined for the alkaloid. 3. The incorporation of 2% hydrochloric acid solution and hot benzene in the extraction procedure appears to facilitate the isolation of kokusaginine. 4. Members of the Rutaceae are significant natural sources of the alkaloid. 5. Pharmacological testing of kokusaginine is being conducted currently.

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Citations
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Journal ArticleDOI

Screening of Mexican Medicinal Plants for Antiprotozoal Activity

TL;DR: Five plant extracts derived from Acalypha phleoides, Cnidoscolus tehuacanensis, Geranium niveum, Hellianthella quinquenervis and Teloxys graveolens were found to possess significant activity against both protozoa, but were less potent than metronidazole.
Journal ArticleDOI

Antimicrobial and cytotoxic activities of some crude drug extracts from Mexican medicinal plants.

TL;DR: The results of the quantitative study indicated that the extracts derived from five species possessed significant antiseptic properties, therefore supporting the ethnomedical uses of these species.
Journal ArticleDOI

Ptelea trifoliata ssp. trifoliata (Rutaceae) in deciduous forest regions of eastern North America.

TL;DR: In this article, the relationship between floral elements of disjunct segments of the mixed mesophytic forest formation in eastern North America was investigated by comparison of populations ofPtelea trifoliata ssp.trijoliata in nine deciduous forest regions, using thin-layer chromatography as a supplement to morphological data.
Book ChapterDOI

Ptelea trifoliata (Quinine Tree, Hop Tree): In Vitro Culture and the Production of Alkaloids and Medicinal Compounds

TL;DR: Ptelea trifoliata L. (Rutaceae) is a bush of North American origin that has been cultivated in Europe since the eighteenth century and has pharmacological properties (particularly bacteriocidal and cytotoxic activities) due to the presence of coumarins and quinoline alkaloids.
References
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Journal ArticleDOI

Alkaloids of the Australian Rutaceae.

TL;DR: In certain tribes of the family Rutaceae, a relatively high proportion of species have been found to contain alkaloids as mentioned in this paper, which vary widely in character and include representatives of several of the principal structural groups, such as quinoline, iso-quinoline, carboline and imidazole derivatives.
Journal ArticleDOI

The chemical constituents of Australian Flindersia species. V. The constituents of Flindersia maculosa Lindl

TL;DR: From the bark of Flindersia maculosa Lindl, this paper isolated the known alkaloids, kokusaginine and flindersiamine, the new alkaloid, maculine and maculosine, and the known coumarin, collinin, and a triterpene, flindissol.
Journal ArticleDOI

Hawaiian plant studies—IX : The alkaloids of Platydesma campanulata mann

F. Werny, +1 more
- 01 Jan 1963 - 
TL;DR: A tentative structure V is proposed in this paper for 6-methoxydictamnine (Ia); a new dihydrodictamnine named platydesmine (III); and two derivatives of 4-quinolone.
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