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[Lead: histopathological findings in experimental contamination].

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TLDR
The findings showed lesions and lead deposits which confirmed the causative agent as well as its toxic contaminating action and showed lead toxicity and cell deposition of concentrations lower than those regarded as toxic on an experimental model with rats C3Hs.
Abstract
The aim of the present paper is to show lead toxicity and cell deposition of concentrations lower than those regarded as toxic on an experimental model with rats C3Hs., forty five grams-rats were used. A standard diet was administered together with water ad-libitium, containing very low doses of lead acetate which was constantly administered and at fixed periods. Light and electron microscopy were used to study the liver and the spleen. These organs are considered to harbour a great amount of constant macrophages with phagocytic function. The findings showed lesions and lead deposits which confirmed the causative agent as well as its toxic contaminating action.

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Effects of High dose Lead Toxication on Liver, Kidneys, Heart, Brain and Blood in Rabbits: An Experimental Study

TL;DR: In conclusion, deleterious effects observed in liver, kidney and blood in high doses of lead administration with some similarities to chronic oral administration of low doses is observed.
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Evaluation of Lead Hepatotoxicity; Histological, Histochemical and Ultrastructural Study

TL;DR: It could be concluded that chronic exposure to lead imposes a potent toxic effect on liver cells manifested as glycogen depletion, cellular infiltration and liver architecture in the form of initiation of periportal fibrosis that may progress to liver cirrhosis.
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The Possible Protective Role of Vitamin C against Toxicity Induced by Lead Acetate in Liver and Spleen of Adult Albino Rats (Light and Electron Microscopic Study)

TL;DR: Results of the present study revealed that administration lead acetate to rats produced harmful effects on the rat’s liver and spleen; showed distortion of liver architecture with marked vacuolar degeneration of the swollen hepatocytes with cytoplasmic vaculations and condensed pyknotic nuclei.
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Borik asit uygulamasının sıçan böbrek ve testis dokusunda oluşturduğu hasara karşı Omega-3 yağ asitlerinin koruyucu etkisinin histopatolojik olarak incelenmesi

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