Journal ArticleDOI
Major histocompatibility (B) complex control of the growth pattern of v-src DNA-induced primary tumors
Reads0
Chats0
TLDR
The finding that the growth patterns of tumors, induced by v- src DNA inoculation at 6 weeks posthatch, differ in these two lines establishes that the B complex exerts control over tumor growth at the level of a v-src-determined function.About:
This article is published in Virology.The article was published on 1992-11-01. It has received 25 citations till now. The article focuses on the topics: Avian sarcoma virus & Rous sarcoma virus.read more
Citations
More filters
Journal ArticleDOI
Nutritional modulation of immune function in broilers.
TL;DR: This review is concerned with nutritional modulation of immunity in broilers that offers insight for nutritionists and researchers to implement nutritional regimen to reduce the severity of disease and to test or validate nutritional regimens that heighten immunity.
Journal ArticleDOI
Assignment of Rfp-Y to the chicken major histocompatibility complex/NOR microchromosome and evidence for high-frequency recombination associated with the nucleolar organizer region.
Marcia M. Miller,Ronald M. Goto,Robert L. Taylor,Rima Zoorob,Charles Auffray,R. W. Briles,W E Briles,Stephen E. Bloom +7 more
TL;DR: A genetic map can now be drawn for a portion of chicken chromosome 16 with Rfp-Y, encompassing two MHCclass I and three MHC class II genes, separated from the B system by a region containing the NOR and exhibiting highly frequent recombination.
Journal ArticleDOI
Impact of genetics on disease resistance
TL;DR: Future research directions will expand knowledge of the impact of genetics on disease resistance by identifying non-MHC genetic control of resistance and by further elucidating mechanisms regulating expression of genes related to immune response.
Journal ArticleDOI
Brief review of the chicken Major Histocompatibility Complex: the genes, their distribution on chromosome 16, and their contributions to disease resistance.
TL;DR: GGA 16 evolves as a microchromosome devoted to immune defense, with many GGA 16 genes are polymorphic and polygenic, and the structure, distribution, linkages and patterns of polymorphism in these regions are suggested.
Journal ArticleDOI
The chicken major histocompatibility complex and disease
TL;DR: The chicken major histocompatibility complex, or B complex, consists of several clusters of highly polymorphic genes, some of which are associated with disease resistance, and shows associations with response to diseases as diverse as virally induced neoplasia, bacterial, parasitic and auto-immune diseases.
References
More filters
Journal ArticleDOI
Identification of haplotypes of the chicken major histocompatibility complex (B).
W. Elwood Briles,R. W. Briles +1 more
TL;DR: A common haplotype terminology across lines was developed and later published in part to illustrate frequency profiles in inbred parent lines of chickens (Briles 1972) as a consequence of reagent preparation in a genetically diverse chicken colony at Northern Illinois University combined with the typing of chickens.
Journal ArticleDOI
TheB locus (MHC) in the chicken: Association with the fate of RSV-induced tumors
W. M. Collins,W. Elwood Briles,Robert M. Zsigray,W. R. Dunlop,A. C. Corbett,Kathy K. Clark,James L. Marks,Timothy P. McGrail +7 more
TL;DR: The MHC chromosomal region in the chicken appears to exert a crucial role in determining the outcome of RSV-induced tumors and in chickens with terminal tumors, the incidence of metastatic lesions was also significantly associated withB genotypes.
Journal ArticleDOI
Genetic control of Rous sarcoma regression in chickens: Linkage with the major histocompatibility complex
TL;DR: Studies with two closely related inbred chicken strains show that regression of Rous sarcoma virus-induced tumors is a dominantly inherited trait, controlled by a gene within, or closely linked to, the major histocompatibility complex (B region).
Journal ArticleDOI
The Ontogeny of Blood Cells, Complement, and Immunoglobulins in 3- to 12-Week-Old 15I5-B Congenic White Leghorn Chickens
TL;DR: Six partially developed line 15I5-B congenic White Leghorn chicken strains were used to investigate age and B haplotype effects on hematocrit, total and differential leukocyte counts, hemolytic complement, immunoglobulins, and body weights, and the results suggest the difference may be determined by genes in the B complex.
Journal ArticleDOI
Response of B Complex Haplotypes B22, B24, and B26 to Rous Sarcomas
W. M. Collins,N. P. Zervas,N. P. Zervas,W. E. Urban,W. E. Urban,W. E. Briles,W. E. Briles,P. A. Aeed,P. A. Aeed +8 more
TL;DR: Dominance in the response to sarcoma was observed when either the B22 or B26 haplotype combined with the B24 haplotype and compared with the appropriate corresponding homozygotes, and when the B26 heterozygote was compared with B22/B22 and B26/B26 homozygote.
Related Papers (5)
Identification of haplotypes of the chicken major histocompatibility complex (B).
W. Elwood Briles,R. W. Briles +1 more