Journal ArticleDOI
Methimazole Treatment and Acute Pancreatitis: Both Caution and Reassurance Are Needed.
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This article is published in The Journal of Clinical Endocrinology and Metabolism.The article was published on 2020-12-01. It has received 6 citations till now. The article focuses on the topics: Pancreatitis & Propylthiouracil.read more
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Management of Graves’ hyperthyroidism: present and future
TL;DR: Treatment of Graves’ disease relies on antithyroid drugs (ATDs), radioactive iodine (RAI), thyroidectomy, and results from targeted therapies acting on different steps of the autoimmune process are preliminary or preclinical, but promising in medium-to-long perspective.
Journal ArticleDOI
Medical treatment of thyrotoxicosis.
Lorenzo Scappaticcio,Giuseppe Bellastella,Maria Ida Maiorino,Luca Giovanella,Katherine Esposito +4 more
TL;DR: In this paper, the authors provide an updated review on the role of conventional medical therapies [i.e. β-blockers, anti-thyroid drugs (ATDs), corticosteroids, inorganic iodide, perchlorate, cholecystographic agents, lithium, cholestyramine] in the main causes of thyrotoxicosis.
Journal ArticleDOI
The Role of Endoplasmic Reticulum Stress in Cell Injury Induced by Methimazole on Pancreatic Cells
TL;DR: In conclusion, methimazole might have triggered the mechanisms of inflammation or autophagy in the pancreatic cells and there is still a need for in vitro and in vivo studies including other cellular parameters related to apoptosis.
Journal ArticleDOI
Risk of acute pancreatitis with methimazole use: a systematic review and meta-analysis
TL;DR: In this paper, a systematic review and meta-analysis was conducted to evaluate the association between methimazole use and new-onset acute pancreatitis (AP) in four observational studies.
References
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Journal ArticleDOI
2018 European Thyroid Association Guideline for the Management of Graves' Hyperthyroidism
TL;DR: If a patient relapses after completing a course of ATD, definitive treatment is recommended; however, continued long-term low-dose MMI can be considered, and steroid prophylaxis is warranted in Graves’ patients with mild/active orbitopathy receiving RAI.
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Drug-Induced Pancreatitis
Claudia Nitsche,Sandrina Maertin,Jonas A. Scheiber,Christoph A. Ritter,Markus M. Lerch,Julia Mayerle +5 more
TL;DR: Drugs are thought to be a rare cause for acute pancreatitis; however 525 different drugs are listed in the World Health Organization (WHO) database suspected to cause acute Pancreatitis as a side effect and for only 31 of these 525 dugs a definite causality was established.
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Anniversary review: Antithyroid drug therapy: 70 years later
Henry B Burch,David S. Cooper +1 more
TL;DR: The history of the development of the thionamide antithyroid drugs, and their current role in the clinical management of patients with hyperthyroidism, are summarized.
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Safety of long-term antithyroid drug treatment? A systematic review
Fereidoun Azizi,R Malboosbaf +1 more
TL;DR: Long-term ATD treatment is safe, especially in low dose and in adults, indicating that it should be considered as an earnest alternative treatment for GD.