Patent
NS5B HVC polymerase inhibitors
Juan C. Jaen,Jay P. Powers +1 more
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TLDR
In this article, compounds, compositions and methods are provided that are useful in the treatment and prevention of certain viral infections and associated diseases, in particular, the compounds of the invention inhibit the activity of a viral RNA polymerase.Abstract:
Compounds, compositions and methods are provided that are useful in the treatment and prevention of certain viral infections and associated diseases. In particular, the compounds of the invention inhibit the activity of a viral RNA polymerase. The subject methods are particularly useful in the treatment of diseases causes by hepatitis C virus infection.read more
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Hcv protease inhibitors and uses thereof
TL;DR: In this paper, the present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same, as well as a list of acceptable compositions of the same compounds.
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TL;DR: A fused ring compound represented by the following general formula [I]: (wherein the symbols are the same as defined in the description) or a pharmaceutically acceptable salt of the compound; and a hepatitis C virus (HCV) polymerase inhibitor and hepatitis C remedy each containing the compound as mentioned in this paper.
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Novel antiviral agents for enveloped viruses
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Compounds, compositions and methods for treating or preventing viral infections and associated diseases
TL;DR: In this article, compounds, compositions and methods are provided for the treatment and prophylaxis of infections and associated diseases caused by viruses of the Flaviviridae family by administering certain rhodanine derivatives, and analogs thereof, tri-and tetracyclic rhodane alkanoic acids and rhodinine benzoic acids being particularly effective.
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Diketoacid-derivatives as inhibitors of polymerases
TL;DR: Diketoacids of Formula (A) are useful as inhibitors of viral polymerases as discussed by the authors, in particular hepatitis C virus RNA dependent RNA polymerase(HCV RdRp), hepatitis B virus polymerase (HBV pol) and reverse transcriptase of human immunodeficiency virus (HIV RT).
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Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis
TL;DR: Aryl carbonyl is a compound of formula (I) that is useful for the treatment and prevention of circulatory diseases and psychosis as discussed by the authors, however, it is not suitable for medical applications.