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Open AccessJournal ArticleDOI

Parturition and Hypocalcemia Blunts Calcium Signals in Immune Cells of Dairy Cattle

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TLDR
It is concluded that intracellular Ca stores decrease in peripheral blood mononuclear cells (PBMC) before parturition and development of hypocalcemia, which suggests that systemic calcium stress precedes measurable hypocalCEmia, particularly in cows that will develop milk fever.
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This article is published in Journal of Dairy Science.The article was published on 2006-07-01 and is currently open access. It has received 309 citations till now. The article focuses on the topics: Calcium & Milk fever.

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Journal ArticleDOI

The monitoring, prevention, and treatment of milk fever and subclinical hypocalcemia in dairy cows

TL;DR: The physiological factors that cause milk fever and strategies for prevention of milk fever are discussed, focusing on the effects diet cation-anion difference can have on tissue sensitivity to parathyroid hormone.
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Postpartum uterine disease and dairy herd reproductive performance: a review.

TL;DR: More field studies are needed to validate criteria for treatment of metritis, but cows with at least two of RP, fever, dullness, and fetid uterine discharge appear to merit treatment with systemic antibiotics.
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Evaluation of peripartal calcium status, energetic profile, and neutrophil function in dairy cows at low or high risk of developing uterine disease

TL;DR: Neither metritis nor SCH influenced the resumption of estrous cyclicity by 38 DIM, but cows with SCH had a reduced pregnancy rate and a longer interval to pregnancy compared with normocalcemic cows.
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Prevalence of subclinical hypocalcemia in dairy herds.

TL;DR: Cows with serum calcium concentrations >2.0 mM had significantly lower serum non-esterified fatty acids indicating better energy balance than those with subclinical hypocalcemia and may make cows more susceptible to secondary diseases but more research will be required to determine if this is true.
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Prevalence of periparturient diseases and effects on fertility of seasonally calving grazing dairy cows supplemented with concentrates.

TL;DR: Periparturient diseases were highly prevalent in seasonally calving grazing dairies and affected cows had delayed resumption of estrous cyclicity, reduced P/AI, and increased risk of pregnancy loss.
References
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Journal ArticleDOI

Physiological changes at parturition and their relationship to metabolic disorders.

TL;DR: Three basic physiological functions must be maintained during the periparturient period if disease is to be avoided: adaptation of the rumen to lactation diets that are high in energy density, maintenance of normocalcemia, and maintenance of a strong immune system.
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A non-disruptive technique for loading calcium buffers and indicators into cells.

TL;DR: A simple technique which loads Ca2+-selective chelators into the cytoplasm of intact cells in suspension and avoids the disadvantages of previous methods is described.
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Calcium Signaling Mechanisms in T Lymphocytes

TL;DR: The complexity of Ca(2+) signals contains a wealth of information that may help to instruct lymphocytes to choose between alternate fates in response to antigenic stimulation and increase the efficiency and specificity of gene activation events.
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