Proceedings ArticleDOI
Pathways of Blood Clotting Initiation by Cancer Cells
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The article was published on 1979-01-01. It has received 24 citations till now. The article focuses on the topics: Cancer cell.read more
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Journal ArticleDOI
Fibrin as a component of the tumor stroma: origins and biological significance
Harold F. Dvorak,Harold F. Dvorak,Donald R. Senger,Donald R. Senger,Ann M. Dvorak,Ann M. Dvorak +5 more
TL;DR: The current status of fibrin's role in the biology of tumor growth is reviewed, considering such important possiblities as a barrier function to the immune response and possible roles in angiogenesis, desmoplasia, and metastasis.
Journal ArticleDOI
Role of plasma, platelets, and endothelial cells in tumor metastasis
TL;DR: Thrombocytopenic agents were effective in every tumor system and with any experimental model of metastasis, indicating that platelets play a role in this process.
Journal Article
Procoagulant activity associated with plasma membrane vesicles shed by cultured tumor cells.
Harold F. Dvorak,van de Water L,Bitzer Am,Ann M. Dvorak,Deborah J. Anderson,V S Harvey,Bach R,Davis Gl,William C. DeWolf,AC Carvalho +9 more
TL;DR: Data indicate that a wide variety of tumor cells release plasma membrane vesicles with procoagulant activity, which may play an important role in the biology of tumor growth by inducing the local fibrin deposits found in association with many solid tumors.
Journal ArticleDOI
Disseminated intravascular coagulation and related syndromes: a clinical review.
TL;DR: Only by clearly understanding pathophysiologic interrelationships can the clinician and laboratorian appreciate the divergent and wide clinical spectrum of often confusing clinical and laboratory findings in patients with DIC.
Journal ArticleDOI
Idiopathic deep vein thrombosis in an apparently healthy patient as a premonitory sign of occult cancer
TL;DR: It is indicated that there is a correlation between idiopathic DVT and occult cancer and that the majority of the patients at risk may probably be identified early by the score devised, which could identify 83% of the Patients with cancer and 91% of those without malignancy.