Open AccessJournal Article
Quantitative Characterization of Derivatization Effects in Separations Techniques I. Derivatization of Ibuprofen
TLDR
In this paper, a distinguished study of chiral recognition and derivatization procedures is presented, where the structure, partition coefficients, enthalpy, entropy, and free entropy change of inclusion complex formations of enantiomers have been compared.Abstract:
Quantitative relations were studied between chiral separation parameters and chemical forms of ibuprofen. The structure, partition coefficients, enthalpy, entropy and free enthalpy change of inclusion complex formations of enantiomers have been established. Results of different methods were compared. The authors emphasis distinguished study of chiral recognition and the derivatization procedures.read more
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Theoretical aspects of chiral separation in capillary electrophoresis: I. Initial evaluation of a model
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