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Open AccessJournal ArticleDOI

Recomendaciones para la monitorización de antibióticos en pacientes críticos ingresados en UCI

Grupo de Estudio de Infección en el paciente crítico, +1 more
- 01 Mar 2008 - 
- Vol. 32, Iss: 2, pp 113-123
TLDR
The purpose of these guidelines is to develop a process of monitoring plasma antimicrobial concentrations that is as homogeneous as possible to facilitate the design of multicenter studies, as well as the interpretation and comparison of results.
About: 
This article is published in Farmacia Hospitalaria.The article was published on 2008-03-01 and is currently open access. It has received 7 citations till now. The article focuses on the topics: Blood sampling.

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Antimicrobial Activity of Fosfomycin-Tobramycin Combination against Pseudomonas aeruginosa Isolates Assessed by Time-Kill Assays and Mutant Prevention Concentrations.

María Díez-Aguilar, +7 more
- 01 Oct 2015 - 
TL;DR: Fosfomycin-tobramycin can be an alternative for infections due to P. aeruginosa since it has demonstrated synergistic and bactericidal activity in susceptible isolates and those with low-level tobramYcin resistance, and it prevents the emergence of resistant mutants in either aerobic or anaerobic environments.
Journal ArticleDOI

Evaluation of population pharmacokinetic models for amikacin dosage individualization in critically ill patients

María del Mar Fernández de Gatta, +5 more
- 01 Jun 2009 - 
TL;DR: Evaluated the reliability for dosage individualization and Bayesian adaptive control of several literature‐retrieved amikacin population pharmacokinetic models in patients who were critically ill.
Journal ArticleDOI

Vancomycin-Induced Acute Kidney Injury Detected by a Prospective Pharmacovigilance Program From Laboratory Signals

Elena Ramírez, +8 more
- 01 Jun 2013 - 
TL;DR: Renal function and vancomycin trough levels should be closely monitored from the second week of treatment in adults, intensive care patients, and those who receive concurrent nephrotoxic agents.
Journal Article

[Pharmacoeconomic analysis of the treatment of methicillin-resistant Staphylococcus aureus with daptomycin or vancomycin].

Carlos Rubio-Terrés, +3 more
- 01 Dec 2012 - 
TL;DR: According to this model, daptomycin is more cost-effective than vancomycin in treating MRSA bacteremia, and the higher cost of acquisition of d aptomycin does not imply aHigher cost of treating this infection.
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Erratum to: 39th ESCP European symposium on clinical pharmacy & 13th SFPC congress: clinical pharmacy at the front line of innovations. 21–23 October 2010, Lyon, France

E. E. Gerbrands
- 29 Sep 2011 - 
TL;DR: This abstract should have been included in the abstract set and is therefore not included.
References
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Journal ArticleDOI

Clinical Response to Aminoglycoside Therapy: Importance of the Ratio of Peak Concentration to Minimal Inhibitory Concentration

Richard D. Moore, +2 more
- 01 Jan 1987 - 
TL;DR: It is demonstrated that a high peak concentration relative to the MIC for the infecting organism is a major determinant of the clinical response to aminoglycoside therapy.
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Pharmacodynamics of Vancomycin and Other Antimicrobials in Patients with Staphylococcus aureus Lower Respiratory Tract Infections

Pamela A. Moise-Broder, +3 more
- 01 Jan 2004 - 
TL;DR: Vancomycin AUC24/MIC values predict time-related clinical and bacteriological outcomes for patients with lower respiratory tract infections caused by methicillin-resistant S. aureus by using data gathered from a therapeutic monitoring environment that observes failures in some cases.
Journal ArticleDOI

The Pharmacokinetic and Pharmacodynamic Properties of Vancomycin

Michael J. Rybak
- 01 Jan 2006 - 
TL;DR: The pharmacokinetic and pharmacodynamic data related to vancomycin are reviewed and such clinical issues as toxicities and serum concentration monitoring are discussed.
Journal ArticleDOI

Pharmacodynamics of Levofloxacin: A New Paradigm for Early Clinical Trials

Sandra L. Preston, +8 more
- 14 Jan 1998 - 
TL;DR: Exposure to levofloxacin was significantly associated with successful clinical and microbiological outcomes and occurrence of adverse events in infected patients and could be used to determine optimal treatment dose in clinical trials in a shorter time frame with fewer patients.
Journal ArticleDOI

Experience with a once-daily aminoglycoside program administered to 2,184 adult patients.

David P. Nicolau, +5 more
- 01 Mar 1995 - 
TL;DR: An ODA program at this institution that utilizes a fixed 7-mg/kg intravenous dose with a drug administration interval based on estimated creatinine clearance appears to be clinically effective, reduces the incidence of nephrotoxicity, and provides a cost-effective method for administration of aminoglycosides by reducing ancillary service time and serum am inoglycoside determinations.