Research note: some observations on experimental avian encephalomyelitis.

TLDR: This study compared the infectivity, incubation period, and clinical response of standard-bred chicks, chicks of different inbred lines, turkey poults, and adult quail to AE virus inoculation, and recorded observations on four serial passages of AE virus in suckling mice.

Abstract: Avian encephalomyelitis (AE) is a widespread virus disease of young chickens, characterized by incoordination, bilateral ataxia, paresis, and, in some cases, head and neck tremors. Experimentally, the disease has been produced by different routes of inoculation in chickens. Natural infection has been reported only in chickens, pheasants, and coturnix quail. Turkey poults, ducklings, squabs, and guinea fowl have been infected experimentally with AE virus (7). Feibel et al. (1) observed some differences in susceptibility between different breeds of chickens and their sex-linked crosses. This study compared the infectivity, incubation period, and clinical response of standard-bred chicks, chicks of different inbred lines, turkey poults, and adult quail to AE virus inoculation, and recorded observations on four serial passages of AE virus in suckling mice.