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Journal ArticleDOI

Simultaneous Sinus Floor Elevation and Implant Placement Using Leukocyte- and Platelet-Rich Fibrin as a Sole Graft Material

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TLDR
L-PRF as a sole graft material during simultaneous SFE and implant placement proved to be a practical, safe, and economical subsinus graft material, resulting in natural bone formation.
Abstract
Purpose Sinus floor elevation (SFE) and simultaneous implant placement is predictable and reproducible. However, the graft material for the antral cavity remains a topic of debate. Considering the high osteogenic potential of the sinus membrane, most graft materials are generally accepted. This study aimed to assess the outcome of simultaneous SFE and implant placement, using leukocyte- and platelet-rich fibrin (LPRF) as a sole graft material. Materials and methods This study was designed as a single cohort prospective study. Clinical and radiographic measurements (cone beam computed tomography [CBCT]) were performed immediately after implant placement and at abutment connection (6 months later). The amount of newly formed bone was linearly recorded on cross-sectional images. Four measurements (mesial, distal, buccal, palatal) were registered with the axis of the implant as reference. Results Six lateral and 22 transalveolar SFEs were performed in 26 patients with simultaneous implant placement. Six months after surgery, 27/29 implants were clinically integrated. The mean vertical bone gain was 3.4 ± 1.2 mm and 5.4 ± 1.5 mm for transalveolar SFE and lateral SFE, respectively. The level of the new sinus floor was in all cases in continuation with the apex of the implant, and the peri-implant crestal bone height was stable. Conclusion L-PRF as a sole graft material during simultaneous SFE and implant placement proved to be a practical, safe, and economical subsinus graft material, resulting in natural bone formation.

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Journal ArticleDOI

Platelet-Rich Plasma in Maxillary Sinus Augmentation: Systematic Review

TL;DR: The use of PRF with other grafting biomaterials appears to provide no additional beneficial effects in sinus lift procedures, but they may improve the healing period and bone formation.
Journal ArticleDOI

Deciphering the secretome of leukocyte-platelet rich fibrin: towards a better understanding of its wound healing properties.

TL;DR: This is the most detailed proteome analysis of the L-PRF secretome to date, and proteins related to platelet and neutrophil degranulation, and their kinetics provide novel information to further understand the wound healing properties of L- PRF.
Journal ArticleDOI

Emerging roles of platelet concentrates and platelet-derived extracellular vesicles in regenerative periodontology and implant dentistry

TL;DR: The clinical application of platelet concentrates and P-EVs for implant surgery and periodontal tissue regeneration are reviewed.
Journal ArticleDOI

Effects of platelet-rich fibrin on osteogenic differentiation of Schneiderian membrane derived mesenchymal stem cells and bone formation in maxillary sinus

TL;DR: In this article , the authors investigated whether mesenchymal stem cells (MSCs) exist in Schneiderian membrane and the effect of platelet-rich fibrin (PRF) on osteogenic differentiation of these cells and on new bone formation in maxillary sinus after MSFE.
Journal ArticleDOI

Lateral Sinus Floor Elevation in the Severely Atrophied Maxilla: Concentrated Growth Factors Versus Bone Substitutes. A Controlled Clinical Trial.

TL;DR: Within the limitations of the present study, the lateral sinus floor elevation performed with the use of CGFs as the sole grafting material showed implant survival rates and marginal bone level changes comparable to DBBM grafting.
References
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Journal Article

Maxillary and sinus implant reconstructions.

TL;DR: The root and sinus series of the Omnii system have been used extensively and their design attempts to maximize the use of the available bone, and placement techniques allow the manipulation of bone to form sockets in otherwise deficient areas of bone.
Journal ArticleDOI

A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation

TL;DR: The insertion of dental implants in combination with maxillary sinus floor elevation is a predictable treatment method showing high implant survival rates and low incidences of surgical complications.
Journal Article

A new concept in maxillary implant surgery: the osteotome technique.

TL;DR: The author concludes that the osteotome technique is superior to drilling for many applications in soft maxillary bone and allows more implants to be inserted in a greater variety of sites during a routine office procedure.
Journal ArticleDOI

A systematic review of post-extractional alveolar hard and soft tissue dimensional changes in humans.

TL;DR: Human re-entry studies showed horizontal bone loss of 29-63% and vertical bone Loss of 11-22% after 6 months following tooth extraction, which demonstrated rapid reductions in the first 3-6 months that was followed by gradual reductions in dimensions thereafter.
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