Journal ArticleDOI
Statins for coronary patients exposed to wildfire-related air pollution - an opportunity to lower the increased risk of coronary events.
Alpo Vuorio,Petri T. Kovanen +1 more
TLDR
Hadley et al. as discussed by the authors found that even very short-term exposure to ambient fine particulate pollution caused by PM2.5 does associate with increased cardiovascular morbidity, and that inhaled particles enter the circulation and then cause low degree inflammation, systemic endothelial dysfunction, and deterioration of vascular health.References
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Journal ArticleDOI
Simvastatin Improves Disturbed Endothelial Barrier Function
Geerten P. van Nieuw Amerongen,Mario A. Vermeer,Pascale Nègre-Aminou,Jan Lankelma,Jef J. Emeis,Victor W.M. van Hinsbergh +5 more
TL;DR: The data show that simvastatin, in a relatively high concentration, improves disturbed endothelial barrier function both in vitro and in vivo, and support the beneficial effects of simVastatin in acute coronary events by mechanisms other than its lipid-lowering effect.
Journal ArticleDOI
Protecting Cardiovascular Health From Wildfire Smoke
TL;DR: In this article , the authors provide a roadmap of evidence-based interventions to reduce risk and protect cardiovascular health, including preparing health systems for smoke events, identifying and educating vulnerable patients, reducing outdoor activities, creating cleaner air environments, using air filtration devices and personal respirators; and aggressive management of chronic diseases and traditional risk factors.
Journal ArticleDOI
Protecting Cardiovascular Health From Wildfire Smoke
TL;DR: This work finds substantial evidence that short-term exposures to wildfire smoke are associated with key cardiovascular outcomes, including mortality, hospitalization, and acute coronary syndrome, and provides a roadmap of evidence-based interventions to reduce risk and protect cardiovascular health.
Journal ArticleDOI
Endothelial dysfunction predicts bleeding and cardiovascular death in acute coronary syndrome.
Tomohiro Yoshii,Yasushi Matsuzawa,So Kato,Ryosuke Sato,Youhei Hanajima,Shin Kikuchi,Hidefumi Nakahashi,Masaaki Konishi,Eiichi Akiyama,Yugo Minamimoto,Yuichiro Kimura,K. Okada,Nobuhiko Maejima,Noriaki Iwahashi,Toshiaki Ebina,Kiyoshi Hibi,Masami Kosuge,Toshihiro Misumi,Kouichi Tamura,Kazuo Kitamura +19 more
TL;DR: In this article , the authors investigated the association of endothelial dysfunction with major bleeding and specific causes of death in addition to major adverse cardiovascular events in patients with acute coronary syndrome, and found that the endothelium dysfunction group patients had a 2.5-fold greater risk of cardiovascular death; however, no association was found with non-cardiovascular death.
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