Studies on the Synthesis of 3-Alkyl-5, 6, 7, 8-tetrahydro-s-triazolo [4, 3-b] [1, 2, 4] triazine-6, 7-diones.
Kiyoshi Futaki,Senji Tosa +1 more
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The chemical structure of the compounds found by the reaction of cyanogen bromide and acylhydrazines was determined as 2-alkyl-5-amino-1, 3, 4-oxadiazoles (I), 3-Alkyl-5, 6, 7, 8-tetrahydro-s-triazolo [4, 3-b] [1, 2, 4] triazine-6, 7-diones (III), which are listed in Table III, were prepared from 4, 5-diaminoAbstract:
The chemical structure of the compounds found by the reaction of cyanogen bromide and acylhydrazines was determined as 2-alkyl-5-amino-1, 3, 4-oxadiazoles (I). 3-Alkyl-5, 6, 7, 8-tetrahydro-s-triazolo [4, 3-b] [1, 2, 4] triazine-6, 7-diones (III), which are listed in Table III, were prepared from 4, 5-diamino-1, 2, 4-triazoles (II) and diethyl oxalate. Several unreported intermediates of these compounds - 2-alkyl-5-amino-1, 3, 4-oxadiazoles (I) and 4, 5-diamino-1, 2, 4-triazoles (II)-were also prepared and are listed in Tables I and II.read more
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Book ChapterDOI
Recent Advances in 1, 3, 4-Oxadiazole Chemistry
A. Hetzheim,K. Möckel +1 more
TL;DR: The 1,3,4-oxadiazole system has an electronic spectrum equivalent to that of benzene and the maxima of the oxadiazoles derivatives are only slightly shifted hypsochromically compared with benzene as mentioned in this paper.
Patent
Triazolotriazine compounds and uses thereof
Zhang Fang-Jie,Tomas Vojkovsky,Ping Huang,Congxin Liang,Steven Do,Marcel Koenig,Jingrong Cui +6 more
TL;DR: The present invention relates to compounds of the Formula (I), and their pharmaceutically acceptable salts as mentioned in this paper, which modulate the activity of c-Met and are therefore expected to be useful in the prevention and treatment of cmet related disorders such as cancer.
Journal ArticleDOI
Competing ring-photoisomerization pathways in the 1,2,4-oxadiazole series. An unprecedented ring-degenerate photoisomerization.
TL;DR: The irradiation of some 5-alkyl-3-amino-1,2,4-oxadiazoles at lambda = 254 nm in methanol in the presence of triethylamine (TEA) gave ring-photoisomerization both into 2-alksyl-5-aminos 1,3, 4-oxADiazoles and, unprecedently, into the ring-degenerate 3-alkYL-5,amino 1,2
Book ChapterDOI
Prototropic tautomerism of heteroaromatic compounds. iv. five-membered rings with two or more hetero atoms.
A.R. Katritzky,J.M. Lagowski +1 more
TL;DR: The tautomerism of compounds with five-membered rings and two or more heteroatoms is more complex than that which occurs when only one heteroatom is present.
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