The aim of this research was to determine acute toxicity of the essential oil derived from aerial parts of Boenninghausenia sessilicarpa Levl. (Rutaceae) against two grain storage insects, maize weevils ( Sitophilus zeamais Motsch.) and red flour beetles ( Tribolium castaneum Herbst.). Essential oil of B. sessilicarpa aerial parts was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry (GC-MS). A total of 42 components of the essential oil were identified. The principal compounds in the essential oil were αcadinol (11.97%), carvacrol (8.77%), germacrene D (6.17%), o-cymene (6.13%), 4-terpineol (5.71%), and αpinene (5.53%). The essential oil exhibited strong contact toxicity against S. zeamais and T. castaneum adults with LD 50 value of 15.25 and 6.02 µg/adult, respectively. The results indicated that the essential oil B. sessilicarpa aerial parts showed potential in terms of acute toxicity against grain storage insects.

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https://wwmw.academicjournals.org/article/article1380870889_Liu et al.pdf

The chemical constituents of boenninghausenia sessilicarpa

Chemical composition and toxicity of essential oil of Boenninghausenia sessilicarpa (Rutaceae) against two grain storage insects

In this study, a preparative countercurrent chromatography (CCC) method for isolation and purification of the bioactive component rutin directly from the ethanol extract of Boenninghausenia sessilicarpa was successfully established by using n-butanol-ethyl acetate-water as the two-phase solvent system. The upper phase of n-butanol-ethyl acetate-water (4:1:5, v/v) was used as the stationary phase of CCC. Under the optimum conditions, 112 mg of rutin at 98.6% purity was obtained from 2.0 g of the crude extract in a single CCC separation. The peak fraction of CCC was identified by negative ESI, 1H NMR, and 13C NMR.

One Step Large-Scale Separation and Purification of Rutin from Boenninghausenia sessilicarpa by Countercurrent Chromatography

4-Substituted coumarin compounds having the general formula of where R is H, CHO, OCH3, X, NO2, an alkyl having C1-10, —OCH2O—, an aryl being mono- or poly-substituted with CN or COOCH3 with the aryl being a phenyl, naphthyl, or azaryl, or a coumarin group that is substituted with R1, R2, R3, R4, with R1, R2, R3, and R4 being H, an alkyl having C1-10, X, NO2, CN, OCH3, COOCH3 or OR5, R5 being H or an alkyl having C1-10, and X being a halogen.

Coumarin compounds and method for preparing and using the same

4-Substituted coumarin compounds having the general formula of
 
wherein R is a phenyl, naphthyl, or azaryl substituted with 2-CHO, or a coumarin group substituted with R 1 , R 2 , R 3 , or R 4 ; R 1 , R 2 , R 3 , and R 4 represent H, C 1-10 alkyl, X, NO 2 , OH, CN, OCH 3 , COOCH 3 or OR 5 respectively; R 2 and R 3 may also together be -OCH 2 O-; R 5 is H or C 1-10 alkyl; X is halogen. The compounds of the present invention have evident antifungal activities, so that it is possible to be used as a medicament in treatments of fungal infection and some diseases such as whitlow and ringworm of nails.

The chemical constituents of boenninghausenia sessilicarpa

Citations

Chemical composition and toxicity of essential oil of Boenninghausenia sessilicarpa (Rutaceae) against two grain storage insects

One Step Large-Scale Separation and Purification of Rutin from Boenninghausenia sessilicarpa by Countercurrent Chromatography

Coumarin compounds and method for preparing and using the same

Coumarins compounds, the preparation and the use thereof