Book ChapterDOI
The Chemistry of Dinucleoside Polyphosphates
Reads0
Chats0
About:
This article is published in ChemInform.The article was published on 2020-11-25. It has received 5 citations till now.read more
Citations
More filters
Journal ArticleDOI
Diguanosine nucleotide metabolism and the survival of artemia embryos during years of continuous anoxia
Alden H. Warner,James S. Clegg +1 more
TL;DR: It is found that the nucleotide Gp(4)G, present initially in very large amounts, decreased slowly as anoxia continued over the 5.6-year period examined, providing a plausible metabolic pathway leading to the provision of ATP and GTP to meet the needs of endergonic processes in anoxic embryos.
Journal ArticleDOI
Characterization of the P2 receptors on the human umbilical vein endothelial cell line ECV304
TL;DR: ECV304 cells display a pharmacology consistent with the presence of at least two P2 receptors; a P2Y2 receptor insensitive to the diadenosine polyphosphates and a P 2Y1 receptor sensitive to Ap3A, and respond to AMP with increases in [Ca2+]c via an as yet uncharacterized receptor.
Journal ArticleDOI
Disruption and overexpression of the Schizosaccharomyces pombe aph1 gene and the effects on intracellular diadenosine 5',5'''-P1, P4-tetraphosphate (Ap4A), ATP and ADP concentrations.
TL;DR: A new S. pombe expression plasmid, pPOX, is described which was used to achieve the largest increase in expression of aph1, which indicates that Aph1 functions in vivo to degrade Ap(4)A, and that high-level overexpression of this enzyme reduces the growth rate.
Journal ArticleDOI
Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Potential relationship with the effect of bisphosphonates on osteoclasts
María A. Günther Sillero,Anabel de Diego,Janeth E.F. Tavares,Joana A.D. Catanho da Silva,Francisco J. Pérez-Zúñiga,Antonio Sillero +5 more
TL;DR: In this paper, the authors showed that T4 RNA ligase, in the presence of ATP and the substrates: geranyl, farnesyl or isopentenyl triphosphates, and Geranyl, Farnesyl, Diphosphate, 6.7, dimethylallyl, 3.1 and isopenta-nyl diphosphates all at 0.3 mM concentration, catalyzed the synthesis of the corresponding ATP derivatives at a relative rate of activity of: 7.6+/-1.4 mU/mg or