Journal ArticleDOI
The effect of (+)-catechin on the hepatic level of ATP and the lipid content of liver during experimental steatosis.
TLDR
The accumulation of NADH and lipids in the liver tissue is also significantly lowered following treatment of the intoxicated rats with (+)-cateehin, and the biochemical mechanism of these effects is discussed.About:
This article is published in Biochemical Pharmacology.The article was published on 1972-02-15. It has received 25 citations till now. The article focuses on the topics: Fatty liver & Steatosis.read more
Citations
More filters
Journal ArticleDOI
Dermal intoxication of mice with bis(2-chloroethyl)sulphide and the protective effect of flavonoids
TL;DR: It is indicated that dermally applied SM can induce lipid peroxidation and GSH depletion, and flavonoids may be beneficial in reducing the toxicity.
Journal ArticleDOI
Protective effect of flavonoids on drug-induced hepatotoxicity in vitro.
TL;DR: Catechin (CAT) and silybin (SIL) protected the hepatocytes against cell injury produced by erythromycin estolate (EE), amitriptyline (AT), nortriptylines (NT), and tert-butylhydroperoxide (TBOOH) and it is suggested that CAT and SIL may act by stabilizing the plasma membrane against toxic insult.
Journal ArticleDOI
Protective effect of (+)cyanidanol-3 in acute liver injury induced by galactosamine or carbon tetrachloride in the rat
D. Perrissoud,I. Weibel +1 more
TL;DR: Pretreatment of rats with (+)cyanidanol-3 decreases the alterations in liver function tests (transaminase and bilirubin) as well as the accumulation of hepatic triglycerides induced by acute doses of galactosamine or carbon tetrachloride.
Journal ArticleDOI
Stereospecific effects of (+)- and (-)-catechin on glycogen metabolism in isolated rat hepatocytes.
TL;DR: In this article, (−)-catechin and (−)-Epicatechin were added to hepatocytes from fasted rats and showed a 90% inhibition of net glycogen production, while (−)-Catechin antagonized the inhibitory action of suboptimal doses of glucagon on glycogen.
References
More filters
Journal ArticleDOI
Metabolism of neoplastic tissue. VI. Assay of oxidized and reduced diphosphopyridine nucleotide in normal and neoplastic tissues.
Journal ArticleDOI
Fatty livers induced by orotic acid. II. Changes in nucleotide metabolism.
TL;DR: An analysis of the fate of dietary erotic acid and the levels of purine and pyrimidine nucleotides in the livers of rats fed various supplemented diets, as well as studies of the formation of nucleotide and the catabolism of orotate in liver slices and cell-free extracts are presented.
Journal Article
The prevention of fatty liver by administration of adenosine triphosphate.
TL;DR: It is observed that a variety of agents which produce a fatty liver lead to decreased ATP concentrations in the liver and that the protective effects of ATP administration are not limited to ethionine toxicity.
Journal ArticleDOI
Prevention of fatty liver by administration of adenosine triphosphate.
D. E. Hyams,Kurt J. Isselbacher +1 more
TL;DR: It has been shown that the fatty liver produced in rats by ethionine administration is associated with a decrease in hepatic adenosine triphosphate (ATP) levels.