Journal ArticleDOI
The effect of cytochalasin B, colchicine and vinblastine on the adhesion of Trichomonas vaginalis to glass surfaces.
P. Cappuccinelli,L. Varesio +1 more
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TLDR
Findings suggest that Trichomonas vaginalis adhesion is at least partially mediated by the extension of cellular probes, due to the action of cytochalasin-sensitive microfilaments.About:
This article is published in International Journal for Parasitology.The article was published on 1975-02-01. It has received 14 citations till now. The article focuses on the topics: Cytochalasin & Cytochalasin B.read more
Citations
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Journal ArticleDOI
Specific nature of Trichomonas vaginalis parasitism of host cell surfaces.
J F Alderete,G E Garza +1 more
TL;DR: Parasitism of epithelial cells appears to render this cell type more susceptible than fibroblast cell types to contact-dependent cytotoxicity, and metabolizing T. vaginalis adheres to host cells via parasite surface proteins in a specific receptor-ligand fashion.
Journal ArticleDOI
Contact-dependent cytopathogenic mechanisms of Trichomonas vaginalis.
J N Krieger,J I Ravdin,M F Rein +2 more
TL;DR: Kinetic analysis of target cell killing by trichomonads revealed that the probability of CHO cell death was related to the likelihood of contact with T. vaginalis, supporting the observation by microscopy that trICHomonads kill cells only by direct contact.
Journal ArticleDOI
The interaction of Trichomonas vaginalis and Tritrichomonas foetus with epithelial cells in vitro.
TL;DR: A study of the involvement of trichomonad surface component in the interaction process indicated that cytochalasin B treated-parasites adhere much less to epithelial monolayers than untreated parasites.
Journal ArticleDOI
Phagocytosis and Killing of Neisseria gonorrhoeae by Trichomonas vaginalis
TL;DR: Type 2 and 4 transparent and opaque Neisseria gonorrhoeae demonstrated a logarithmic loss of viability with a half life of approximately 10-30 min when incubated in the presence of Trichomonas vaginalis, and this effect was observed in the absence of serum for most types of gonococci tested, but was consistently enhanced by the addition of human serum.
Book ChapterDOI
Biochemistry of Trichomonas vaginalis
TL;DR: It would be premature, however, to go beyond pointing out that the nutrient-rich, largely anaerobic environment, and the properties of the organism living in it, are well matched to each other.
References
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Journal ArticleDOI
Microfilaments in Cellular and Developmental Processes
Norman K. Wessells,Brian S. Spooner,J. F. Ash,M. O. Bradley,Marilyn A. Ludueña,E. L. Taylor,Joan T. Wrenn,Kenneth M. Yamada +7 more
TL;DR: The overall conclusion is that a broad spectrum of cellular and developmental processes are caused by contractile apparatuses that have at least the common feature of being sensitive to cytochalasin.
Journal ArticleDOI
The establishment of various trichomonads of animals and man in axenic cultures
Journal ArticleDOI
Acanthamoeba Myosin I. ISOLATION FROM ACANTHAMOEBA CASTELLANII OF AN ENZYME SIMILAR TO MUSCLE MYOSIN
Thomas D. Pollard,Edward D. Korn +1 more
TL;DR: An ATPase that accounts for about 0.3% of the total cell protein has been isolated in 90% purity from Acanthamoeba castellanii and shows some activity toward nucleoside triphosphates other than ATP but does not hydrolyze ADP or AMP.
Journal ArticleDOI
Microfilaments and cell locomotion.
TL;DR: The role of microfilaments in generating cell locomotion has been investigated in glial cells migrating in vitro and removal of cytochalasin results in complete recovery of migratory capabilities, even in the absence of virtually all protein synthesis.
Journal ArticleDOI
Microtubular crystals in mammalian cells
TL;DR: Periwinkle alkaloids in very low concentrations cause an intracytoplasmic sequestration of microtubule protein in the form of symmetrical, microtubular bodies; neither colchicine nor puromycin prevents the formation of these bodies; the latter compound retards crystal growth.
Related Papers (5)
Contact-dependent cytopathogenic mechanisms of Trichomonas vaginalis.
J N Krieger,J I Ravdin,M F Rein +2 more
Specific nature of Trichomonas vaginalis parasitism of host cell surfaces.
J F Alderete,G E Garza +1 more
Pathogenic Trichomonas vaginalis cytotoxicity to cell culture monolayers
John F. Alderete,Eric Pearlman +1 more