The genetic‐determination of ossification sequence polymorphism
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Findings support the contention that the major part of variation in ossification sequence is genetically determined.Abstract:
Serial hand-wrist x-rays of 81 pairs of twins were examined to investigate the genetics of ossification sequence polymorphism. Discordance in ossification sequence was 3.5 times more common between like-sex dizygotic twins than between monozygotic twins, with the difference being significant at the 0.01 level of confidence. These findings support the contention that the major part of variation in ossification sequence is genetically determined.read more
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References
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Journal ArticleDOI
Variability in the order of ossification of the bony centers of the hand and wrist.
Journal ArticleDOI
Ossification sequence polymorphism and sexual dimorphism in skeletal development.
TL;DR: Ossification sequence polymorphism is more clearly defined in later-developing children, where the appearance of ossification centers is distributed among a larger number of radiographic class intervals, and may explain the apparent relationship between ossifying sequence polymophism and developmental delay or retardation.
Journal ArticleDOI
Genetics of hand-wrist ossification.
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Degree of kinship and pattern of ossification. A longitudinal X‐ray study of the appearance pattern of ossification centers in children of different kinship groups
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Parent-Child Similarities in Hand-Wrist Ossification
TL;DR: A familial syndrome involving the disproportionately late appearance of a cluster of carpal centers and twin similarities in both the sequences of hand ossification and epiphyseal union is described.