T
Thomas Blumenthal
Researcher at University of Colorado Boulder
Publications - 179
Citations - 10645
Thomas Blumenthal is an academic researcher from University of Colorado Boulder. The author has contributed to research in topics: Gene & Caenorhabditis elegans. The author has an hindex of 50, co-authored 178 publications receiving 10314 citations. Previous affiliations of Thomas Blumenthal include University of Colorado Denver & Indiana University.
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C. Elegans II
TL;DR: For example, it has become increasingly clear over the past two decades that knowledge from one organism, even one so simple as a worm, can provide tremendous power when connected with knowledge from other organisms.
Journal ArticleDOI
The genome sequence of Caenorhabditis briggsae: A platform for comparative genomics
Lincoln Stein,Zhirong Bao,Zhirong Bao,Darin Blasiar,Thomas Blumenthal,Michael R. Brent,Nansheng Chen,Asif T. Chinwalla,Laura Clarke,Chris Clee,Avril Coghlan,Alan Coulson,Alan Coulson,Peter D'Eustachio,Peter D'Eustachio,David H. A. Fitch,Lucinda Fulton,Robert E Fulton,Sam Griffiths-Jones,Todd W. Harris,LaDeana W. Hillier,LaDeana W. Hillier,Ravi Kamath,Patricia E. Kuwabara,Elaine R. Mardis,Marco A. Marra,Marco A. Marra,Tracie L. Miner,Patrick Minx,James C. Mullikin,James C. Mullikin,Robert W. Plumb,Jane Rogers,Jacqueline E. Schein,Jacqueline E. Schein,Marc Sohrmann,John Spieth,Jason E. Stajich,Chaochun Wei,David Willey,Richard K. Wilson,Richard Durbin,Robert H. Waterston,Robert H. Waterston +43 more
TL;DR: Comparisons of the two genomes exhibit extensive colinearity, and the rate of divergence appears to be higher in the chromosomal arms than in the centers, which will help to understand the evolutionary forces that mold nematode genomes.
Journal ArticleDOI
A global analysis of Caenorhabditis elegans operons
Thomas Blumenthal,Donald Evans,Christopher D. Link,Alessandro Guffanti,Daniel Lawson,Jean Thierry-Mieg,Danielle Thierry-Mieg,Wei Lu Chiu,Kyle Duke,Moni Kiraly,Stuart K. Kim +10 more
TL;DR: The evidence indicates that the genome contains at least 1,000 operons, 2–8 genes long, that contain about 15% of all C. elegans genes, and inspection of the operon list should reveal previously unknown functional relationships.
Journal ArticleDOI
RNA replication: function and structure of Qbeta-replicase.
TL;DR: Overcoming Template Specificity in Q/3 RNA replication is overcome and recognition of Synthetic RNAs isrecognition of Synthetics RNAs.
Journal ArticleDOI
Operons in C. elegans: Polycistronic mRNA precursors are processed by trans-splicing of SL2 to downstream coding regions
TL;DR: Evidence is presented that the genes in these clusters are cotranscribed and downstream mRNAs are formed by cleavage at the polyadenylation site and trans-splicing, suggesting that polycistronic RNAs can be processed by trans- Splicing.