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Open AccessJournal ArticleDOI

The Location Of Escherichia Coli In The Pig Intestine

J. B. R. Arbuckle
- 01 May 1970 - 
- Vol. 3, Iss: 2, pp 333-340
TLDR
It is considered that adhesion of E. coli to small-intestinal villi is a significant lesion of porcine diarrhoea associated with enteropathogenic strains of E.
Abstract
Summary The situation of enteropathogenic strains of Escherichia coli in the porcine intestine of naturally occurring and experimentally reproduced cases of E. coli diarrhoea was studied mainly by fluorescent staining techniques. Three different enteropathogenic strains were found on villi of the small intestine, but only small numbers of these bacteria were found on the colonic mucosa except when they were contiguous with the mass of bacteria in the lumen. A non-entero-pathogenic strain of E. coli was found on villi of the small intestine in small numbers. Occasional Gram-positive bacilli were observed on a few villi in the intestines of two healthy piglets. Coliform attachment to villi was found to be most marked when diarrhoea was clinically well established, but such attachment was also sometimes observed during the early clinical stages of diarrhoea. It is therefore considered that adhesion of E. coli to small-intestinal villi is a significant lesion of porcine diarrhoea associated with enteropathogenic strains of E. coli.

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Plasmid-controlled colonization factor associated with virulence in Esherichia coli enterotoxigenic for humans.

TL;DR: It was demonstrated that E. coli H-10407, but not H10407-, possessed pilus-like surface structures which agglutinated with the specific adsorbed (anti-colonization factor) antiserum, which may play an important and possibly essential role in naturally occurring E coli enterotoxic diarrhea in man.
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Observations On The Pathogenic Properties Of The K88, Hly And Ent Plasmids Of Escherichia Coli With Particular Reference To Porcine Diarrhoea

TL;DR: Bacteriological examinations on the animals given the different forms of the O141:K85ab,88ab, the O8:K40, 88ab:H9 and the O9:K36:H19 strains revealed that it was the K88 antigen that enabled the organisms to proliferate high up in the small intestine, an essential prerequisite in the pathogenesis of E. coli diarrhea.
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Host-specific fimbrial adhesins of noninvasive enterotoxigenic Escherichia coli strains.

TL;DR: Adhesins of Human Enterotoxigenic E. coli Strains are characterized by high adhesion to Intesinal Epithelial Cells, and the nature of the Receptor Sites for Adhesins is explained.
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Role of the K88 Antigen in the Pathogenesis of Neonatal Diarrhea Caused by Escherichia coli in Piglets

TL;DR: The results show that K88 antigen is responsible for attachment of K88-positive bacteria to the wall of the small intestine, and that adhesion is essential for the virulence of K 88- positive bacteria in conventionally reared piglets.
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