The meniscus--can it be repaired? An experimental investigation in rabbits
TLDR
In rabbits, repair of incisions in the central part of the meniscus has been demonstrated after surgical excision of the peripheral rim and transformation of fibrous tissue into fibrocartilage has also been observed.Abstract:
In rabbits, repair of incisions in the central part of the meniscus has been demonstrated after surgical excision of the peripheral rim. Healing took place via a highly cellular but relatively avascular fibrous tissue stroma which proliferated from the synovial margin and invaded along the cut edge of the meniscus. Suturing facilitated this healing process by providing stability and possibly by supplying bridges for synovial cells to migrate onto the meniscus. Transformation of fibrous tissue into fibrocartilage has also been observed.read more
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Microvasculature of the human meniscus
TL;DR: The microvascular anatomy of the medial and lateral menisci of the human knee was investigated in 20 cadaver specimens by histology and tissue clearing (Spalteholz) techniques and it was found that the men is supplied by branches of the lateral, medial, and middle genicular arteries.
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The microvasculature of the meniscus and its response to injury An experimental study in the dog
TL;DR: The normal vascular anatomy of the menisci was investigated in five dogs by histology and tissue-clearing techniques and this response originated from the peripheral synovial tissues and completely healed the lesion with fibrovascular scar tissue by 10 weeks.
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The menisci of the knee joint. Anatomical and functional characteristics, and a rationale for clinical treatment
Karola Messner,Jizong Gao +1 more
TL;DR: There is no proof that replacement of the meniscus with an allograft can reestablish some of the important meniscal functions, and thereby prevent or reduce the development of osteoarthrosis which is common after meniscectomy.
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Homologous meniscus transplantation. Experimental and clinical results.
TL;DR: The increase in severe ligament injuries of the knee has led to consideration of the need for meniscal transplantation in reconstructive operations for chronic rotational instability, and both types of transplanted menisci, lyophilised and deep frozen, decreased in size.
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Histological Changes in the Human Anterior Cruciate Ligament After Rupture
TL;DR: After rupture, the human anterior cruciate ligament undergoes four histological phases, consisting of inflammation, epiligamentous regeneration, proliferation, and remodeling, which is similar to that reported in other dense connective tissues.