Institution
Hospital for Special Surgery
Healthcare•New York, New York, United States•
About: Hospital for Special Surgery is a healthcare organization based out in New York, New York, United States. It is known for research contribution in the topics: Arthroplasty & Population. The organization has 5440 authors who have published 12013 publications receiving 472144 citations.
Papers published on a yearly basis
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University of New South Wales1, Hospital for Special Surgery2, Hokkaido University3, University of Utah4, University of Texas Health Science Center at San Antonio5, Utrecht University6, University of Milan7, Geneva College8, Sheba Medical Center9, University of Brescia10, National and Kapodistrian University of Athens11
TL;DR: This document appraise the existing evidence on clinical and laboratory features of APS addressed during the forum and proposes amendments to the Sapporo criteria, including definitions on features ofAPS that were not included in the updated criteria.
5,699 citations
TL;DR: The estimated relative risk of death from an increase of one in the comorbidity score proved approximately equal to that from an additional decade of age.
5,388 citations
TL;DR: A new total knee rating system has been developed by The Knee Society to provide an up-to-date more stringent evaluation form and eliminates the problem of declining knee scores associated with patient infirmity.
Abstract: A new total knee rating system has been developed by The Knee Society to provide an up-to-date more stringent evaluation form. The system is subdivided into a knee score that rates only the knee joint itself and a functional score that rates the patient's ability to walk and climb stairs. The dual rating system eliminates the problem of declining knee scores associated with patient infirmity.
4,505 citations
St. Jude Children's Research Hospital1, University of Edinburgh2, Singapore Immunology Network3, New York University4, University College London5, Heidelberg University6, University of Oxford7, Royal Melbourne Hospital8, Hospital for Special Surgery9, University of Milan10, Aix-Marseille University11, University of Maryland, College Park12, European Institute of Oncology13, Massachusetts Institute of Technology14, University of Bonn15, University of Maryland, Baltimore16, University of Eastern Piedmont17, University of Louisville18, Vrije Universiteit Brussel19, National Institutes of Health20
TL;DR: A set of standards encompassing three principles-the source of macrophages, definition of the activators, and a consensus collection of markers to describe macrophage activation are described with the goal of unifying experimental standards for diverse experimental scenarios.
4,287 citations
TL;DR: In this paper, the authors summarize the signalling and epigenetic mechanisms that regulate type I IFN-induced STAT activation and ISG transcription and translation and conclude that these regulatory mechanisms determine the biological outcomes of type I ILN responses and whether pathogens are cleared effectively or chronic infection or autoimmune disease ensues.
Abstract: Type I interferons (IFNs) activate intracellular antimicrobial programmes and influence the development of innate and adaptive immune responses. Canonical type I IFN signalling activates the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway, leading to transcription of IFN-stimulated genes (ISGs). Host, pathogen and environmental factors regulate the responses of cells to this signalling pathway and thus calibrate host defences while limiting tissue damage and preventing autoimmunity. Here, we summarize the signalling and epigenetic mechanisms that regulate type I IFN-induced STAT activation and ISG transcription and translation. These regulatory mechanisms determine the biological outcomes of type I IFN responses and whether pathogens are cleared effectively or chronic infection or autoimmune disease ensues.
2,273 citations
Authors
Showing all 5601 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Stephen J. O'Brien | 153 | 1062 | 93025 |
| Lloyd J. Old | 152 | 775 | 101377 |
| Richard B. Devereux | 144 | 962 | 116403 |
| Thomas J. Walsh | 131 | 991 | 84597 |
| Henrik Kehlet | 130 | 1069 | 76338 |
| Russell F. Warren | 128 | 647 | 50685 |
| Scott L. Friedman | 126 | 488 | 62931 |
| Csaba Szabó | 123 | 958 | 61791 |
| Charles S. Lieber | 120 | 647 | 50420 |
| Kenneth H. Mayer | 115 | 1351 | 64698 |
| Jeffrey N. Katz | 114 | 695 | 56439 |
| Michael B. Brenner | 111 | 393 | 44771 |
| Barbara B. Kahn | 103 | 281 | 53325 |
| Mary J. Roman | 100 | 365 | 48687 |
| Thomas A. Einhorn | 94 | 330 | 32850 |