Three-Dimensional Simulation of the Ventricular Depolarization and Repolarization Processes and Body Surface Potentials: Nornal Heart and Bundle Branch Block

TLDR: A three-dimensional computer model has been constructed to simulate the ventricular depolarization and repolarization processes in a human heart, and the resulting ECG, VCG, and BSPM's are within the expected range of clinical observations.

Abstract: A three-dimensional computer model has been constructed to simulate the ventricular depolarization and repolarization processes in a human heart. The electrocardiogram (ECG), the vectorcardiogram(VCG), and the body surface potential map (BSPM) during the QRS-T period are obtained automatically under certain heart conditions such as bundle branch block and myocardial infarctions. The ventricles, together with bundle branches and the Purkinje fibers, are composed of approximately 50 000 cell units which are arranged in a cubic close-packed structure. A different action potential waveform was assigned to each unit. The heart model is mounted in a homogeneous human torso model. Electric dipoles, which are proportional to the spatial gradient of the action potential, are generated in all the cell units. These dipoles give rise to a potential distribution on the torso surface, which is calculated by means of the boundary element method. The resulting ECG's, VCG's, and BSPM's are within the expected range of clinical observations.