Journal ArticleDOI
Three-dimensional spinal deformity in scoliosis associated with cerebral palsy and with progressive muscular dystrophy.
Shigeo Suzuki,Yoshitaka Kasahara,Satoru Yamamoto,Yoichi Seto,Kengo Furukawa,Yoshihito Nishino +5 more
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TLDR
There was a correlation between the magnitude of Cobb angle and that of the vertebral rotation in scoliosis associated with both CP and PMD, but the ratio of spinal rotation to Cobb angle in the former was lower than that in the latter.Abstract:
The authors analyzed lateral deviation, anteroposterior deformity, and rotation of the spinal column of 11 patients with scoliosis associated with cerebral palsy (CP) and 11 patients with progressive muscular dystrophy (PMD). There was a correlation between the magnitude of Cobb angle and that of the vertebral rotation in scoliosis associated with both CP and PMD, but the ratio of spinal rotation to Cobb angle in the former was lower than that in the latter, The magnitudes of thoracic kyphosis and of lumbar lordosis were not correlated with Cobb angle in either group, but the sagittal plane deformity in the CP patients was less severe than that in the PMD patients, and the latter demonstrated kyphosis of the lumbar spine and lordosis of the thoracic spine.read more
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Natural history of scoliosis in spastic cerebral palsy
TL;DR: The natural history of scoliosis from childhood through to adulthood is clarified and objective data on proper surgical indications for such patients with severe spastic cerebral palsy is provided and patients with these risk factors might benefit from early surgical intervention to prevent progression to severeScoliosis.
Journal ArticleDOI
Severe osteogenesis imperfecta in cyclophilin B-deficient mice.
Jae Won Choi,Shari L. Sutor,Lonn D. Lindquist,Glenda L. Evans,Benjamin J. Madden,H. Robert Bergen,Theresa E. Hefferan,Michael J. Yaszemski,Richard J. Bram +8 more
TL;DR: Post translational prolyl-3-hydroxylation of type I collagen by P3H1 was essentially absent in CypB-deficient cells and tissues from CypB–knockout mice, providing significant new mechanistic insight into the pathophysiology of OI.
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Spinal deformities following selective dorsal rhizotomy.
Jeff D Golan,Jeffery A. Hall,Gus O'Gorman,Chantal Poulin,Thierry E. Benaroch,Marie-Andrée Cantin,Jean-Pierre Farmer +6 more
TL;DR: There was a high rate of radiologically documented deformities in patients with CP who underwent SDR and the severity of preoperative CP was identified as an important predictor, and less ambulatory patients were more likely to have scoliotic curves.
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Lumbar Spinal Disorders in Patients With Athetoid Cerebral Palsy: A Clinical and Biomechanical Study
Toshinori Sakai,Hidehiro Yamada,Taro Nakamura,Kazuhisa Nanamori,Yoshiteru Kawasaki,Naoyoshi Hanaoka,Eijiro Nakamura,Ken Uchida,Vijay K. Goel,Lakshmi Vishnubhotla,Koichi Sairyo +10 more
TL;DR: The FEM based results showed that stresses at pars interarticularis of L5 were the highest of all levels in all loading modes, with or without preload, however, compared with the extension or axial rotation alone modes, the combined motion of extension and rotation showed higher stresses at the pars interartsicularis.
Journal ArticleDOI
Correction of sagittal plane spinal deformities with unit rod instrumentation in children with cerebral palsy
TL;DR: Patients with cerebral palsy and a severe sagittal plane deformity (> or =70 degrees ) can be treated successfully with posterior spinal fusion with use of unit rod instrumentation.