Journal ArticleDOI
Ultrasonic characterization of aging in skin tissue
TLDR
It is suggested that the tissue changes which collectively constitute aging may, in some instances, be predictably associated with measurable changes in the acoustic properties of those tissues.Abstract:
The propagation velocity (c) and attenuation coefficient (α) of ultrasound were measured at room temperature in skin tissues excised from twenty aged (27 months) and eight young (2 months) Bar Harbor strain female mice. Frequencies used were 2.25, 5.0, 7.5 and 10.0 MHz. Both velocity and attenuation data were obtained using a pulse-echo technique. Transit times were measured with a universal counter timer to 10 nsec resolution, and corrected for the “dead time” due to the transducer matching layer. Aged skin had significantly lower values of c and α at all frequencies than did the corresponding young tissues. This preliminary study suggests that the tissue changes which collectively constitute aging may, in some instances, be predictably associated with measurable changes in the acoustic properties of those tissues.read more
Citations
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Journal ArticleDOI
Ultrasonic propagation properties of excised human skin.
TL;DR: Strong correlation existed between integrated backscatter and fibrous protein content in the epidermis but not in the dermis, and the mean attenuation coefficients obtained for whole skin agreed well with previously published results.
Book ChapterDOI
Acoustic Properties of Tissue at Ultrasonic Frequencies
TL;DR: In this article, the authors discussed the properties of tissue at ultrasonic frequencies, although there is also a brief mention of transmission properties at audio frequencies, and the total attenuation in tissue results from the combined losses as a result of absorption and scattering and can be expressed by the equation: α = α a + α s, where α a is the amplitude absorption coefficient and α s are the amplitude scattering coefficient.
Journal ArticleDOI
High-frequency ultrasonic attenuation and backscatter coefficients of in vivo normal human dermis and subcutaneous fat
TL;DR: In vivo attenuation and backscatter coefficients of normal human forearm dermis and subcutaneous fat were determined in the ranges 14 to 50 MHz and 14 to 34 MHz, respectively using three different transducers to ensure that results were independent of the measurement system.
Journal ArticleDOI
What dermatologists should know about digital imaging.
TL;DR: Dermatologists should understand certain basic concepts about images and imaging techniques to take advantage of progress in this field and eventually apply it to their own research and/or clinical practice.
Journal ArticleDOI
Ultrasound backscatter microscope analysis of mouse melanoma progression.
Daniel H. Turnbull,Daniel H. Turnbull,Daniel H. Turnbull,Jennifer A. Ramsay,Gulnar Shivji,Timothy S. Bloomfield,Lynn From,Daniel N. Sauder,F. Stuart Foster +8 more
TL;DR: It is demonstrated the first application of an imaging method called ultrasound backscatter microscopy (UBM) for imaging early murine melanomas with spatial resolution of 30 microns axial and 60 microns lateral, and the relative error in UBM-determined volume was shown to be less than 17%.
References
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Journal ArticleDOI
Comprehensive compilation of empirical ultrasonic properties of mammalian tissues
TL;DR: A detailed review of the literature on ultrasonic propagation properties of mammalian tissues and organs has revealed 144 papers containing compilable data, including over 1300 lines of parametric data.
Journal ArticleDOI
Tabular Data of the Velocity and Absorption of High‐Frequency Sound in Mammalian Tissues
D. E. Goldman,T. F. Hueter +1 more
TL;DR: This report is a condensed presentation of currently available data on the velocity and absorption of high‐frequency sound in mammalian tissues.
Journal ArticleDOI
Absorption and dispersion of ultrasound in biological tissue
TL;DR: Experimental data indicate that absorption and dispersion in biological materials are due to relaxation processes distributed over a range of frequencies, including solvent-solute interactions and disturbances in H-bonding equilibria.
Journal ArticleDOI
Frontiers of Matrix Biology
TL;DR: This volume is largely a collection of reviews of previously published work by a number of American and European investigators of elastin biology, and surprisingly little new informational concepts are presented in the monograph.
Journal ArticleDOI
Ultrasonic attenuation in human tissue.
R.C. Chivers,C.R. Hill +1 more
TL;DR: Measurements of attenuation as a continuous function of frequency between 1·0 and 7·5 MHz presented for fixed human fat, liver and spleen at 18°C are compared with data from the literature, showing approximate agreement for liver, whilst for fat the values are significantly higher than those previously reported.