Journal ArticleDOI
Whipple's disease: a review of 19 patients from one hospital and a review of the literature since 1950
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This article is published in Medicine.The article was published on 1970-05-01. It has received 244 citations till now. The article focuses on the topics: Whipple's disease & Whipple Disease.read more
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Journal ArticleDOI
Whipple's disease.
TL;DR: Major advances made recently in techniques for detecting and isolating the causative agent may show that Whipple's disease is more common and has a broader clinical spectrum than was previously thought.
Journal ArticleDOI
Cultivation of the Bacillus of Whipple's Disease
Didier Raoult,Marie L. Birg,Bernard La Scola,Pierre E. Fournier,M. Enea,Hubert Lepidi,Véronique Roux,Jean-Charles Piette,François Vandenesch,Denis Vital-Durand,Thomas J. Marrie +10 more
TL;DR: The bacterium of Whipple's disease was cultivated, specific antibodies in tissue from the source patient were detected and generated in mice to be used in the immunodetection of the microorganism in tissues, and the development of a serologic test for Whipples disease may now be possible.
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Whipple's Disease: New Aspects of Pathogenesis and Treatment
Thomas Schneider,Verena Moos,Christoph Loddenkemper,Thomas Marth,Florence Fenollar,Didier Raoult +5 more
TL;DR: The epidemiology of Whipple's disease and the recent progress made in the understanding of its pathogenesis and the biology of its agent are reviewed and procedures for the improvement of diagnosis and an optimum therapeutic strategy are suggested.
Journal ArticleDOI
Whipple disease. Clinical review of 52 cases. The SNFMI Research Group on Whipple Disease. Société Nationale Française de Médecine Interne.
TL;DR: A retrospective clinical study of 52 patients recruited in various parts of France from 1967 to 1994 confirms the central role of an uncultured Gram-positive bacillus which was named in 1992 Tropheryma whippelii in Whipple disease.
Journal ArticleDOI
Whipple's Disease: Clinical, Biochemical, and Histopathologic Features and Assessment of Treatment in 29 Patients
TL;DR: In an analysis of a 30-year, 29-patient experience with Whipple's disease at the Mayo Clinic, the frequent initial manifestations of diarrhea, weight loss, arthritis, and lymphadenopathy correlated with findings reported previously by other investigators.