Examples of article 3 section 5?5 answersArticle 3(5) of the Treaty on the European Union is a significant provision that pertains to EU external relations and was introduced as part of the Lisbon Treaty. This provision has attracted attention from scholars due to its emphasis on 'strict observance and the development of close relations with neighboring countries'. Additionally, the Employment Non-Discrimination Act (ENDA) in the United States aims to prevent discrimination against LGB and T individuals, allowing state employees to take legal action against states for such discrimination. However, concerns have been raised regarding potential conflicts with state sovereign immunity and the need for Congress to demonstrate past state violations of constitutional rights before subjecting states to lawsuits. These examples highlight the legal complexities and implications associated with Article 3(5) and similar legislative measures in different jurisdictions.
What is the toxic dose of diphenhydramine?4 answersThe toxic dose of diphenhydramine is dose-dependent, with a critical dose limit of 1.0 g. Symptoms of toxicity can occur above ingested doses of 0.3 g, with severe symptoms occurring above 1.0 g. However, the relationship between ingested dose and symptom severity is insignificant. It is important to note that toxicity can occur even with the use of diphenhydramine in large doses or via the intravenous route. Additionally, diphenhydramine has been shown to have a protective effect against organophosphorus insecticide-induced toxicosis.
What is hdac3?]?5 answersHDAC3 is a histone deacetylase enzyme that plays a crucial role in various biological processes. It is highly expressed in lung tissues and macrophages, and its activation is associated with acute lung injury (ALI). HDAC3 is involved in mediating pyroptosis, a form of cell death, in macrophages through the activation of the cyclic GMP-AMP synthase (cGAS)/stimulator of interferon genes (STING) pathway. Additionally, HDAC3 is known to regulate oxidative stress-related processes and molecules, mitochondrial function, and metabolism. In the context of cancer, HDAC3 has been found to be required for lung tumor growth and to enhance the transcription effects of the lung cancer lineage transcription factor NKX2-1. Furthermore, HDAC3 is involved in the regulation of adipose tissue physiology and its genetic inactivation leads to metabolic reprogramming of white adipocytes towards browning.
Is there a link between pld3 gene and dip2a gene?5 answersThere is no direct mention of a link between the PLD3 gene and the DIP2A gene in the provided abstracts.
What is the common concentration of Diphenyleneiodonium chloride in experiment?5 answersThe common concentration of Diphenyleneiodonium chloride in experiments is not mentioned in the provided abstracts.
What does an odds ratio of 3.3 mean?10 answers