What are the standard anti-inflammatory test protocols used in clinical practice?4 answersStandard anti-inflammatory test protocols in clinical practice involve a combination of clinical and laboratory findings. Molecular diagnostics, particularly RT-PCR, have emerged as crucial methods for assessing inflammatory markers like IL-6, TNF-α, and IL-10. Additionally, dietary interventions play a significant role in managing inflammation, with an emphasis on consuming anti-inflammatory foods while avoiding proinflammatory ones. Research has identified various common dietary plants and mushrooms with potent anti-inflammatory properties, which could potentially be utilized to limit inflammation in age-related diseases. Overall, a comprehensive approach combining clinical assessments, molecular diagnostics, and dietary interventions is essential for effectively monitoring and managing inflammation in clinical settings.
Which food has anti-inflammatory properties?5 answersGrapefruit (Citrus paradisi) has been found to have anti-inflammatory properties. Marine sources, including microalgae, macroalgae, crustaceans, fish, and fish by-products, also contain compounds with anti-inflammatory effects. Edible bird's nests (EBN) have been identified as potential food therapy for inflammation, including anti-inflammatory agents against SARS-COV-2. A recipe extract based on the leaves of Ceiba pentandra, Ipomoea batatas, and Spinacia oleracea has been shown to have anti-inflammatory activity. Additionally, a functional food mixture containing Cuscuta seeds and Lactobacillus paracasei NK112 has demonstrated anti-neuroinflammatory effects.
Is cocoa anti-inflammatory?3 answersCocoa and cocoa polyphenols have been shown to have anti-inflammatory effects in the context of obesity and cardiometabolic disease in both animal models and humans. However, there is a lack of evidence of antinociceptive effects of cocoa from clinical trials in humans. Cocoa extract, rich in epicatechin, inhibits the growth, biofilm formation, adherence, and hydrogen sulfide production of Fusobacterium nucleatum, a bacterium associated with periodontal diseases. Acute cocoa consumption decreases adhesion molecules and leukotrienes, and regular consumption may reduce inflammation by lowering the activation of monocytes and neutrophils. Cocoa polyphenols may reduce exercise-induced oxidative stress but not inflammation, and the effects on exercise performance and recovery are mixed. In summary, while cocoa and cocoa polyphenols have shown anti-inflammatory effects in certain contexts, further research is needed to establish their efficacy in humans and their role in exercise-mediated inflammation.
Does concentrations of medicinal plants extract influence anti-inflammatory activity?5 answersThe concentration of medicinal plant extracts can influence their anti-inflammatory activity. Several studies have investigated the anti-inflammatory effects of different plant extracts and their bioactive compounds. For example, the methanol extract of Marrubium alysson showed the best inhibitory activity against butyrylcholinesterase (BChE). Additionally, the methanol extracts of Marrubium alysson and Peganum harmala exhibited the highest anti-inflammatory activity. Furthermore, the methanol and petroleum ether leaf extracts of Momardica charantia, Citrullus lanatus, Coccinia grandis, and Lagenaria siceraria were studied for their anti-inflammatory activity, indicating the potential of these plants in treating inflammation. These findings suggest that the concentration of medicinal plant extracts can play a role in their anti-inflammatory effects, with higher concentrations potentially leading to stronger activity.
Do phytochemicals have anti-inflammatory properties?2 answersPhytochemicals have been shown to possess anti-inflammatory properties. They can regulate oxidative stress and inflammation, which are key factors in the progression of inflammatory diseases such as diabetic nephropathy (DN). Epigenetic modifications, including histone modification, DNA methylation, and post-transcriptional miRNA-mediated modifications, play a role in inducing or suppressing inflammatory signaling. Phytochemicals have been found to target these epigenetic alterations and attenuate inflammatory dysregulations. In the case of diabetic retinopathy (DR), phytochemicals with anti-inflammatory, antiangiogenic, and antioxidant properties have been shown to prevent the progression of DR and protect against retinal damage. Additionally, phytochemicals from Aegle marmelos have demonstrated significant anti-inflammatory and antioxidant activity, making them potential treatments for oxidative stress and inflammation.
What is the best natural anti inflammatory for rheumatoid arthritis?9 answers