Can mycobacterium tuberculosis be detected in breath?
Best insight from top research papers
Mycobacterium tuberculosis can be detected in breath using various methods. One study examined a point-of-care breath analyzer called TSI-3000(I) and found it to be a reliable screening tool for TB detection, with a sensitivity of 95.7% and a specificity of 91.3% . Another study tested exhaled breath condensate (EBC) samples and found that the presence of Mtb-specific lipids, lipoarabinomannan lipoglycan, and proteins in EBCs can efficiently differentiate TB patients from controls . A proof-of-concept study explored a breath test using high-pressure photon ionization time-of-flight mass spectrometry (HPPI-TOFMS) and found that it could distinguish latent tuberculosis infection (LTBI) from controls with a sensitivity of 80.0% and a specificity of 80.8% . Multiple studies have shown that breath tests, including those using electronic-nose devices, can accurately diagnose TB, although further development is needed for real-time test results . Overall, these findings suggest that mycobacterium tuberculosis can indeed be detected in breath using different approaches.
Answers from top 5 papers
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| Papers (5) | Insight |
|---|---|
| Yes, mycobacterium tuberculosis can be detected in breath using breath tests with electronic-nose and other devices. | |
01 Apr 2022 | Yes, mycobacterium tuberculosis can be detected in breath using exhaled breath condensate (EBC) analysis. |
| Yes, mycobacterium tuberculosis can be detected in breath using exhaled breath condensate (EBC) samples. | |
| Yes, a breath test using high-pressure photon ionization time-of-flight mass spectrometry (HPPI-TOFMS) can detect Mycobacterium tuberculosis in breath. | |
| Yes, mycobacterium tuberculosis can be detected in breath using a point-of-care breath analyzer that detects volatile organic compounds emitted from infected cells. |
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