scispace - formally typeset
Search or ask a question

Effect of low protein diet on health, diseases and organ? 


Best insight from top research papers

A low-protein diet has various effects on health and diseases. Research indicates that low-protein diets can lead to improved growth but may result in mild hepatic steatosis. In chronic kidney disease (CKD) patients, a low-protein diet can help manage the condition, reduce proteinuria, and delay the need for dialysis. Additionally, in non-dialysis CKD patients, a low-protein diet has shown benefits in improving cardiovascular risk factors such as overweight and plasma lipid profile. Studies have also highlighted that a protein-restricted diet may reduce the rate of decline in renal function and the risk of kidney failure in CKD populations. These findings emphasize the significant impact of low-protein diets on various aspects of health, particularly in conditions like CKD and hepatic steatosis.

Answers from top 4 papers

More filters
Papers (4)Insight
A low protein diet can benefit chronic kidney disease by reducing kidney failure risk, slowing renal function decline, and decreasing proteinuria, serum phosphorus, and BMI levels.
Open accessJournal ArticleDOI
11 Jan 2017
26 Citations
A low-protein diet can preserve kidney function, improve hyperphosphatemia and hyperkalemia, reduce complications, and prolong the hemodialysis-free interval, benefiting overall health and kidney-related diseases.
Low-protein diet in non-dialysis CKD patients improved lipid profiles, reduced BMI, cholesterol, and uric acid levels, suggesting benefits for cardiovascular health in this population.
A low-protein diet can ameliorate proteinuria, delay dialysis initiation in CKD, improve serum albumin levels, reduce metabolic burden, oxidative stress, and phosphorus burden, aiding in managing chronic kidney diseases.

Related Questions

What are the relationship between low protein diet and glycogen metabolism in muscle?5 answersA low-protein diet during critical developmental periods can have lasting effects on glycogen metabolism in muscle. Studies show that maternal low-protein diets lead to reduced glycogen synthesis in skeletal muscle, impacting glucose uptake and oxidation. Additionally, protein-deficient rats exhibit alterations in glucose metabolism, with reduced glycogen synthesis in the soleus muscle, which can be restored with chronic aerobic exercise. Furthermore, low-carbohydrate diets have been linked to impaired muscle glycogen concentrations and synthesis, affecting anaerobic performance. These findings highlight the intricate relationship between protein intake, glycogen metabolism, and muscle function, emphasizing the importance of adequate protein and carbohydrate intake for optimal muscle health and performance.
Does eating protein cause weight gain?5 answersProtein intake, especially in early childhood, has been associated with weight gain and an increased risk of obesity later in life. High protein intake, particularly from dairy sources, has been linked to greater weight gain and BMI in children. However, the specific role of different protein sources in weight gain is still being investigated. Short-term consumption of a high protein diet has been shown to cause weight loss and prevent weight regain. On the other hand, long-term consumption of high-protein diets may have detrimental effects on health, increasing the risk of insulin resistance, diabetes, cardiovascular disease, and chronic kidney disease. Therefore, while protein intake can contribute to weight gain, the effects may vary depending on the source and duration of consumption.
What is the effect of a high protein diet on the hunger system?4 answersA high protein diet has been shown to have an effect on the hunger system. Studies have demonstrated that high protein diets can reduce hunger and increase feelings of fullness or satiety. This effect may be due to the release of hormones such as glucagon-like peptide-1 (GLP-1), cholecystokinin, and peptide tyrosine-tyrosine, which reduce appetite. Additionally, high protein diets have been found to increase satiety signaling and reduce food intake. The increased satiety may be attributed to factors such as the higher diet-induced thermogenesis of proteins compared to carbohydrates and fats, as well as the preservation of fat-free mass, which helps maintain resting energy expenditure despite weight loss. However, further studies are needed to confirm these results and to better understand the mechanisms behind the hunger-reducing effects of high protein diets.
How does protein impact the overall health?4 answersProtein has a significant impact on overall health. It is essential for growth, development, and maintenance of the human body. Adequate consumption of high-quality proteins from animal products is crucial for optimal growth, development, and health. Protein plays a role in promoting skeletal muscle protein accretion and physical strength. It also contributes to efficient macronutrient utilization and storage. Higher protein intakes can help prevent age-related muscle loss and improve satiety, weight management, and athletic performance. Food proteins have specific biological activities that can influence cardiovascular health, bone health, weight management, and sports performance. Overall, protein is a vital nutrient that provides essential amino acids, energy, and various health benefits, making it crucial for overall health and well-being.
How much protein should a person eat per day?5 answersA person should consume approximately 90-100 g of protein per day, primarily from animal sources, despite the increasing need for vegetable protein. Animal feed with insufficient protein leads to higher fodder consumption, increasing the need for plant protein. The EFSA Panel on Dietetic Products recommends an average protein requirement of 0.66 g/kg body weight per day for healthy adults, with a Population Reference Intake (PRI) of 0.83 g/kg body weight per day. Meeting the daily protein recommendation of ≥1.0 g/kg/day is associated with decreased odds of functional disability in older Americans. The indicator amino acid oxidation (IAAO) method suggests that minimum protein requirements have been underestimated by 30-50%, and a variety of high-quality proteins at a range of 1.5-2.2 g/(kg·day) is suggested.
Can low protein cause low platelets?5 answers

See what other people are reading

What are the most effective treatment strategies for hypotension in different clinical settings?
5 answers
Effective treatment strategies for hypotension vary across different clinical settings. In critical care situations, interventions like fluid bolus therapy and vasopressors are common treatments, but the choice of intervention can be challenging. For clozapine-induced hypotension, temporary dose reduction, non-pharmacological interventions, and medications like midodrine and fludrocortisone have shown efficacy. In hemodialysis patients, early prediction and management of intradialytic hypotension can be improved through new biomarkers, volume assessment devices, biofeedback systems, and personalized nursing strategies. During cesarean sections under neuraxial anesthesia, preventive measures like vasopressors, elastic compression of lower extremities, and co-infusion of crystalloids are recommended for managing arterial hypotension. Overall, a combination of pharmacological and non-pharmacological approaches tailored to the specific clinical context is crucial for effectively treating hypotension.
What are the current statistics and trends regarding Sudden Unexpected Infant Deaths?
5 answers
Sudden Unexpected Infant Death (SUID) rates have shown varying trends and disparities. While the SIDS rate increased in 2020, the overall SUID rate did not change significantly, with diagnostic shifting likely explaining the rise in SIDS cases. Nationally, non-Hispanic Black infants have double the risk of SUID compared to non-Hispanic White infants, with disparities magnified in certain cities. Histological examinations are crucial in understanding sudden infant deaths, revealing underlying diseases that may not be visible externally. SUID mortality rates have been decreasing in the US, with an inverse relationship to immunization coverage, although the decline has slowed since 1996. Unsafe sleep environments are common in both explained and unexplained SUID cases, emphasizing the need for improved investigations to identify high-risk infants.
What are the leading causes of SUIDs, particularly focusing on accidental suffocation in bed?
5 answers
Accidental suffocation in bed, particularly due to overlay or wedging, is a significant cause of sudden unexpected infant deaths (SUIDs). Factors contributing to accidental suffocation include bed sharing, makeshift bedding arrangements, and exposure to intoxicated or sedated parents. The lack of consistent investigation practices and diagnostic challenges make it difficult to differentiate between sudden infant death syndrome (SIDS) and accidental suffocation. Studies suggest that infants sharing a sleeping surface have different characteristics compared to those sleeping alone, indicating a potential link to suffocation deaths. Accurate monitoring and classification systems are crucial to identify high-risk groups and inform strategies for reducing SUIDs, emphasizing the importance of addressing accidental suffocation in bed as a leading cause of infant mortality.
What are the theoretical concepts behind fasting during Ramadan?
5 answers
Fasting during Ramadan is rooted in Islamic principles and serves both spiritual and social goals. Islamic fasting involves abstaining from eating, drinking, and sexual intercourse from before sunrise until after sunset, emphasizing virtues without compromising health. The fasting practice aims to instill endurance, patience, and empathy for the less fortunate, teaching believers to endure hardships and develop self-discipline. While fasting is mandatory for mentally and physically capable adult Muslims, exceptions are made for health reasons like sickness, pregnancy, or travel. Medical science plays a role in determining potential health risks associated with fasting, ensuring individuals' well-being while upholding the spiritual significance of the practice. Overall, fasting during Ramadan intertwines religious devotion with physical well-being, emphasizing balance between spiritual growth and health considerations.
How can humour be used to reduce fear?
5 answers
Humor can be effectively utilized to reduce fear by inducing Rapid Anxiety Reduction (RAR). Studies show that humor therapy sessions significantly decrease state anxiety levels in patients undergoing hemodialysis, offering a low-cost and easy-to-implement complementary therapy. Furthermore, humor has been found to alleviate interpersonal anxiety triggered by gender-related interactions, ultimately reducing fear and improving social outcomes. Reviewing humor interventions for adults, it is evident that planned humor, including various types like indirect, direct, social, and self-humiliating humor, effectively reduces stress, anxiety, and depression. Additionally, humor strategies have been shown to positively impact speaking anxiety in English language learners, highlighting the potential of humor to alleviate fears associated with language proficiency. Overall, humor serves as a powerful tool in mitigating fear and anxiety across various contexts.
Is drug resistance different in function of where the tumor in an organ is?
5 answers
Drug resistance can vary depending on the location of the tumor within an organ. Tumor heterogeneity, driven by genomic mutations and interactions within the tumor microenvironment (TME), plays a crucial role in influencing drug resistance. Spatial and temporal evolution of tumor heterogeneity leads to constant reprogramming of the TME, affecting therapeutic targets and drug efficacy. Additionally, the heterogeneity of drug penetration within the tumor microenvironment can contribute to acquired drug resistance, with sanctuary compartments having poor drug exposure being more prone to resistance development. Understanding the impact of the TME on tumor heterogeneity and drug resistance is essential for developing effective therapeutic strategies tailored to the specific characteristics of the tumor's location within an organ.
Interaction between energy and protein in the nutrient utilization ruminants?
5 answers
The interaction between energy and protein in nutrient utilization in ruminants is crucial for optimizing animal productivity and health. Balancing the supply of nitrogen and energy to rumen microbes is essential for efficient nutrient utilization. Synchronization of rumen-available protein and energy enhances nutrient efficiency in ruminants. Ruminants are anatomically adapted to utilize non-proteinaceous nitrogen compounds, emphasizing the importance of considering both protein and energy sources for effective utilization. New feeding systems focus on digestive interactions to improve predictions of diet responses by integrating energy and protein digestion mechanisms. Understanding the dynamics between energy and protein is key to formulating diets that maximize microbial synthesis efficiency and reduce environmental nitrogen excretion.
How does the prevalence of hypertension in Madagascar compare to other countries in the region?
5 answers
The prevalence of hypertension in Madagascar is notably high and comparable to, if not exceeding, rates observed in other countries within the region. Studies conducted in urban and rural communities of Madagascar have identified a hypertension prevalence of approximately 27.0% in rural areas and 29.7% in urban populations. This is almost double what has been previously found in Madagascar, suggesting a significant increase over time. The high prevalence is consistent with global trends, where hypertension is recognized as a leading preventable cause of premature death worldwide. Comparatively, in Ethiopia, the prevalence of hypertension among adult patients in outpatient departments was found to be 44.91%, indicating a higher prevalence rate than in Madagascar. This suggests that while Madagascar faces a significant burden of hypertension, other countries in the region may experience even higher rates of this condition. The situation in Madagascar is further complicated by low rates of treatment and control. In rural areas, only 1.7% of hypertensive subjects were on antihypertensive treatment, and in urban areas, this figure was slightly higher at 5.3%. This is indicative of a broader issue in sub-Saharan Africa, where most patients with hypertension require two or more drugs to control their blood pressure, yet adherence and access to treatment remain challenges. Moreover, the knowledge and management of hypertension among patients in Madagascar are lacking, with many patients not following recommendations for hypertension management. This is compounded by the increasing prevalence of hypertension and its complications, highlighting a pressing need for improved public health interventions. In summary, while the prevalence of hypertension in Madagascar is alarmingly high and comparable to other countries in the region, it is the low rates of awareness, treatment, and control that underscore the urgent need for enhanced healthcare strategies and public health education to mitigate the impact of this condition.
Do a literature review on Lazarus syndrome?
5 answers
The Lazarus syndrome, also known as autoresuscitation, is a rare phenomenon where spontaneous circulation returns after cessation of resuscitation efforts following cardiac arrest. Initially described in 1982, this phenomenon has been reported in various age groups, with cases showing survival times ranging from minutes to months. Pediatric autoresuscitation is exceptionally rare, with only a few documented cases, challenging the current understanding of death certification and highlighting the need for clearer guidelines. Despite being underreported, the literature emphasizes the importance of monitoring patients post-CPR cessation to prevent autoresuscitation, with recommendations such as continuous observation and ECG monitoring for at least 10 minutes. Further research is needed to better understand and address this intriguing yet uncommon occurrence in medical practice.
What are the primary causes of mortality in Madagascar related to hypertension?
5 answers
The primary causes of mortality in Madagascar related to hypertension are cardiovascular diseases, including stroke, heart failure, and complications arising from hypertensive heart disease. Hypertension, a major risk factor for cardiovascular diseases, is highly prevalent in both urban and rural areas of Madagascar, with significant under-treatment in rural populations, indicating a looming epidemic of cardiovascular diseases as the society ages. The lack of reliable national statistics on causes of death complicates the understanding of mortality trends, but the performance of the death notification system in Antananarivo suggests that cardiovascular diseases are a significant concern. The prevalence of hypertension in rural Madagascar is alarmingly high, similar to urban centers in other African countries, and almost double what has been previously found in Madagascar, suggesting an increasing trend that could contribute to higher mortality rates from related diseases. Stroke, as a direct complication of hypertension, is among the leading causes of death. Hypertensive disorders of pregnancy, including pre-eclampsia, also contribute to maternal and fetal morbidity and mortality, indicating the broader impact of hypertension on public health. Despite the high prevalence of hypertension, adherence to treatment and dietary advice remains low, exacerbating the risk of cardiovascular mortality. Hypertension during pregnancy is a frequent and serious condition, further emphasizing the need for early detection and management to prevent maternal and fetal deaths. Atrioventricular block, often secondary to hypertensive heart disease, highlights the cardiovascular complications of hypertension that can lead to mortality. Hemorrhagic stroke, strongly associated with high blood pressure, is a significant predictor of intra-hospital mortality, underscoring the critical impact of hypertension on stroke mortality. Collectively, these findings underscore the urgent need for improved hypertension management and prevention strategies to mitigate its role in cardiovascular and maternal-fetal mortality in Madagascar.
What is the impact of education for glycemic control?
5 answers
Education plays a crucial role in improving glycemic control among patients with diabetes mellitus (DM). Studies have shown that strategic DM education actions lead to enhanced glycemic control and reduced prevalence of chronic complications. Proper education on insulin injection techniques has been linked to better glycemic control outcomes. Health literacy (HL) interventions have also demonstrated a positive impact on glycemic control and self-management behaviors in type 2 DM patients. The multidisciplinary approach with integrated and quality education has been associated with improvements in DM control and a decrease in chronic DM complications. Therefore, educating patients on diabetes management, including insulin injection techniques and HL interventions, is essential for achieving optimal glycemic control and minimizing complications associated with diabetes.