J
Jing Chen
Researcher at Fudan University
Publications - 132
Citations - 3047
Jing Chen is an academic researcher from Fudan University. The author has contributed to research in topics: Kidney disease & Renal function. The author has an hindex of 24, co-authored 124 publications receiving 2230 citations. Previous affiliations of Jing Chen include Boston Children's Hospital.
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Journal ArticleDOI
Incremental Hemodialysis, Residual Kidney Function, and Mortality Risk in Incident Dialysis Patients: A Cohort Study.
Yoshitsugu Obi,Elani Streja,Connie M. Rhee,Vanessa A. Ravel,Alpesh Amin,Adamasco Cupisti,Jing Chen,Anna T. Mathew,Csaba P. Kovesdy,Csaba P. Kovesdy,Rajnish Mehrotra,Kamyar Kalantar-Zadeh,Kamyar Kalantar-Zadeh,Kamyar Kalantar-Zadeh +13 more
TL;DR: In this article, the authors hypothesized that a less frequent schedule at hemodialysis therapy initiation is associated with greater preservation of RKF without compromising survival among patients with substantial residual kidney function (RKF).
Journal ArticleDOI
Sirt1 Activation Ameliorates Renal Fibrosis by Inhibiting the TGF-β/Smad3 Pathway
Xin-Zhong Huang,Donghai Wen,Min Zhang,Qionghong Xie,Leting Ma,Yi Guan,Yueheng Ren,Jing Chen,Chuanming Hao +8 more
TL;DR: The results identify Sirt1 as an important protective factor for renal fibrosis in a CKD rodent model, and the protective function of Sirt 1 is attributable to its action on TGF‐β/Smad3 signaling.
Journal ArticleDOI
Whole Exome Sequencing of Patients with Steroid-Resistant Nephrotic Syndrome
Jillian K. Warejko,Weizhen Tan,Ankana Daga,David Schapiro,Jennifer A. Lawson,Shirlee Shril,Svjetlana Lovric,Shazia Ashraf,Jia Rao,Tobias Hermle,Tilman Jobst-Schwan,Eugen Widmeier,Amar J. Majmundar,Ronen Schneider,Heon Yung Gee,J. Magdalena Schmidt,Asaf Vivante,Amelie T. van der Ven,Hadas Ityel,Jing Chen,Carolin E. Sadowski,Stefan Kohl,Werner L. Pabst,Makiko Nakayama,Michael J. Somers,Nancy Rodig,Ghaleb Daouk,Michelle A. Baum,Deborah R. Stein,Michael A. J. Ferguson,Avram Z. Traum,Neveen A. Soliman,Jameela A. Kari,Sherif El Desoky,Hanan M. Fathy,Martin Zenker,Sevcan A. Bakkaloglu,Dominik N. Müller,Aytül Noyan,Fatih Ozaltin,Melissa A. Cadnapaphornchai,Seema Hashmi,Jeffrey Hopcian,Jeffrey B. Kopp,Nadine Benador,Detlef Bockenhauer,Radovan Bogdanovic,Natasa Stajic,Gil Chernin,Robert B. Ettenger,Henry Fehrenbach,Markus J. Kemper,Reyner Loza Munarriz,Ludmila Podracka,Rainer Büscher,Erkin Serdaroglu,Velibor Tasic,Shrikant Mane,Richard P. Lifton,Daniela A. Braun,Friedhelm Hildebrandt +60 more
TL;DR: W whole exome sequencing is a sensitive approach toward diagnosis of monogenic causes of steroid-resistant nephrotic syndrome.
Journal ArticleDOI
Twice-weekly and incremental hemodialysis treatment for initiation of kidney replacement therapy.
Kamyar Kalantar-Zadeh,Kamyar Kalantar-Zadeh,Mark Unruh,Philip G. Zager,Csaba P. Kovesdy,Joanne M. Bargman,Jing Chen,Suresh Sankarasubbaiyan,Gaurang M. Shah,Thomas A. Golper,Richard A. Sherman,David S. Goldfarb +11 more
TL;DR: The concept of incremental HD is reviewed, in which weekly dialysis dose, in particular HD treatment frequency, is based on a variety of clinical factors, such as RKF, volume status, cardiovascular symptoms, body size, potassium and phosphorus levels, nutritional status, hemoglobin level, and health-related quality of life.
Journal ArticleDOI
Whole-Exome Sequencing Identifies Causative Mutations in Families with Congenital Anomalies of the Kidney and Urinary Tract.
Amelie T. van der Ven,Dervla M. Connaughton,Hadas Ityel,Nina Mann,Makiko Nakayama,Jing Chen,Asaf Vivante,Daw-Yang Hwang,Julian Schulz,Daniela A. Braun,Johanna Magdalena Schmidt,David Schapiro,Ronen Schneider,Jillian K. Warejko,Ankana Daga,Amar J. Majmundar,Weizhen Tan,Tilman Jobst-Schwan,Tobias Hermle,Eugen Widmeier,Shazia Ashraf,Ali Amar,Charlotte A. Hoogstraaten,Hannah Hugo,Thomas M. Kitzler,Franziska Kause,Caroline M. Kolvenbach,Rufeng Dai,Leslie Spaneas,Kassaundra Amann,Deborah R. Stein,Michelle A. Baum,Michael J. Somers,Nancy Rodig,Michael A. J. Ferguson,Avram Z. Traum,Ghaleb Daouk,Radovan Bogdanovic,Natasa Stajic,Neveen A. Soliman,Jameela A. Kari,Sherif El Desoky,Hanan M. Fathy,Danko Milosevic,Muna Al-Saffar,Muna Al-Saffar,Hazem S. Awad,Loai A. Eid,Aravind Selvin,Prabha Senguttuvan,Simone Sanna-Cherchi,Heidi L. Rehm,Daniel G. MacArthur,Daniel G. MacArthur,Monkol Lek,Monkol Lek,Kristen M. Laricchia,Michael W. Wilson,Shrikant Mane,Richard P. Lifton,Richard P. Lifton,Richard S. Lee,Stuart B. Bauer,Weining Lu,Heiko Reutter,Velibor Tasic,Shirlee Shril,Friedhelm Hildebrandt +67 more
TL;DR: Whole-exome sequencing provides an etiologic diagnosis in a high fraction of patients with CAKUT and will provide a new basis for the mechanistic understanding ofCAKUT.