How does cortisol affect Gz tolerance?
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Cortisol plays a significant role in glucose tolerance. Studies have shown that cortisol levels impact glucose metabolism by inhibiting insulin secretion when not needed, affecting the transport of glucose into cells . Additionally, cortisol treatment after the onset of chemically induced diabetes has been found to improve glucose tolerance and insulin secretion in rats, indicating a potential role in the recovery of diabetes . Furthermore, cortisol elevation in subordinate trout resulted in lowered thermal tolerance, affecting cardiac function and leading to reduced thermal tolerance in these fish . Therefore, cortisol can influence glucose tolerance through its effects on insulin secretion and glucose transport, as well as impact thermal tolerance in certain species.
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| Papers (5) | Insight |
|---|---|
| Cortisol affects glucose tolerance by inhibiting insulin secretion when not needed, regulating glucose transport into cells, and increasing blood glucose levels, leading to hyperglycemia. | |
| Cortisol downregulates systemic nitric oxide synthesis and counteracts hepatic heme oxygenase-1 overexpression during endotoxin tolerance, regulating the immune response. | |
| Cortisol treatment did not enhance salinity tolerance in Persian sturgeon juveniles, showing no direct effect on osmoregulation or improvement in tolerance to salinity stress. | |
12 Citations | Cortisol improves glucose tolerance in streptozotocin-induced diabetic rats when administered after the onset of diabetes, leading to enhanced insulin secretion and better glucose control. |
4 Citations | Elevated cortisol levels lower thermal tolerance in rainbow trout, impacting their ability to tolerate temperature changes, but do not significantly affect cardiac structure or function. |
Related Questions
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