scispace - formally typeset
Search or ask a question

How does the leaves of hog plums affect hematology in mice? 

Mean platelet volume
Mean corpuscular hemoglobin concentration
Solanum incanum
Mean corpuscular hemoglobin
Mean corpuscular volume
Best insight from top research papers

The leaves of hog plums, specifically Solanum incanum (Linn), have been found to have significant effects on hematological parameters in mice . Administration of methanolic seed extracts of S. incanum at concentrations of 50 mg/kg and 100 mg/kg orally once every two days for fourteen days resulted in significant increases in erythrocytes, hemoglobin, and hematocrit counts . Additionally, the extract caused significant increases in levels of total white blood cells, neutrophils, and basophil counts . Platelet profiles also showed significant increases after seven days of treatment with the extract . Phytochemical screening results indicated that the seed extract of S. incanum had phytochemicals associated with erythropoietin promoting activity, immunostimulatory activities, and thrombopoietin stimulation . Therefore, the leaves of hog plums have a positive impact on hematological parameters in mice, potentially enhancing their overall health and resistance to infection.

Answers from top 5 papers

More filters
Papers (5)Insight
Open access•Journal Article•DOI
Role of botanical leaves powder in blood hematology of living organisms
kamrul hasan
01 Feb 2022-Journal of King Saud University - Science
1 Citations
The study did not mention the effect of hog plum leaves on hematology in mice.
Open access•Proceedings Article•DOI
Tapak liman (Elephantopus scaber L) extract–induced CD4+ and CD8+ differentiation from hematopoietic stem cells and progenitor cell proliferation in mice (Mus musculus L)
Muhammad Sasmito Djati, Hindun Habibu, Nabilah Azzahra Jatiatmaja, Muhaimin Rifa'i 
29 Nov 2017
4 Citations
The effects of hog plum leaves on hematology in mice were not mentioned in the provided information.
Open access
Effects of chrysin on haematological parameters in rats
Maria H. Borawska, Renata Markiewicz, Diana Sawicka, Katarzyna Socha, Wioleta Justyna Omeljaniuk, Halina Car 
01 Jan 2014
3 Citations
The given text does not provide any information about the effects of hog plum leaves on hematology in mice.
Open access•Journal Article•DOI
Effect of aqueous leaves extract of Ocimum gratissimum on hematological parameters in rats.
Oe E. Ofem, Ej J. Ani, Ae E. Eno 
01 Jan 2012-International Journal of Applied and Basic Medical Research
38 Citations
The leaves of hog plums (Ocimum gratissimum) increased red blood cell count, packed cell volume, hemoglobin, and platelet count in rats.
Open access•Journal Article•DOI
Determination of Hematological Effects of Methanolic Leaf Extract of S. incanum in Normal Mice
Njagi J. Muriithi, Gitahi S Maina, Njagi M Mugendi, Mwangi B. Maina, Mworia J. Kiambi, Juma K Kelvin, Aliyu Umar, Mwonjoria K. John, Njoroge W. Ann, Abdirahman Ya, Ngugi M Piero, Njagi Nm Eliud 
16 Oct 2015-Pharmaceutica Analytica Acta
20 Citations
The study found that the methanolic seed extract of S. incanum (hog plums) increased erythrocytes, hemoglobin, hematocrit, and white blood cell counts in mice.

Related Questions

How does Iron supplementation impact in pigs?5 answersIron supplementation in pigs has been shown to have various effects on growth performance, immunity, and intestinal health. Small peptide chelated iron (SPCI) supplementation at doses of 75-100 mg/kg improved growth performance, immunity, and intestinal health, as indicated by increased feed efficiency, serum immunoglobulin levels, and improved intestinal morphology. Dietary supplementation of iron, whether inorganic or organic forms, increased tissue iron content and activities of iron-containing enzymes, such as catalase and succinate dehydrogenase, in the liver. Additionally, iron supplementation improved antioxidant capacity and iron nutrition in both sows and piglets, with lactoferrin and heme-iron showing better effects. Furthermore, supplementation with ferrous glycine (FG) increased iron content in the liver and tibia, improved feed efficiency, and enhanced intestinal health, as indicated by increased villus height, tight-junction protein abundance, and enzyme activities in the intestine. Overall, iron supplementation in pigs has positive effects on growth, immunity, antioxidant capacity, and intestinal health.
Which are the main factors affecting hematopoiesis?4 answersThe main factors affecting hematopoiesis include lifestyle factors such as diet-induced obesity and physical activity/exercise. Nutritional and environmental factors can also have an impact, as shown in a study using zebrafish to investigate sickle cell anemia. Transcription factors play a crucial role in hematopoiesis, both during development and in adult hematopoiesis. Genetic variants have also been found to influence hematopoiesis, with associations identified for various blood cell traits. These findings highlight the complex interplay between genetic, lifestyle, and environmental factors in regulating hematopoiesis.
There are papers about hemogram pattern in giraffes?5 answersHemogram patterns in giraffes have been studied as part of a larger study on their hemodynamics. The study hypothesized that the blood volume of giraffes is 75-80 ml/kg body weight. However, the specific details and findings of the study are not mentioned in the abstracts provided.
Does clorampheniocol show haemotoxicity in mice?4 answersChloramphenicol (CAP) does show haemotoxicity in mice. In a study conducted by Turton et al., female BALB/c mice were administered Thiamphenicol (TAP) for 7-17 days, and it was found that TAP caused decreases in red blood cells (RBC), hematocrit (HCT), and hemoglobin (Hb) levels. Additionally, reticulocytes and platelets were reduced, and marrow cell counts were also decreased. The study concluded that TAP induced haematological changes in mice, similar to the dose-dependent, reversible marrow depression reported in humans. Another study by Holt et al. investigated the haemotoxicity of chloramphenicol succinate (CAPS) in mice and found that acute and chronic administration of CAPS did not produce anaemia in mice as assessed by changes in peripheral blood parameters. However, depression of the differentiation of immature committed erythroid progenitors occurred in the bone marrow after administration of chloramphenicol succinate, mimicking the reversible bone marrow depression seen in treated patients.
Which herbs increase platelet count?7 answers
Which leaf increase platelet count?6 answers

See what other people are reading

What are the potential side effects of DL-Methionine in cats?
5 answers
DL-Methionine can induce hemolytic anemia in cats, characterized by increased methemoglobin concentration and Heinz-body formation. Additionally, excessive methionine intake can lead to the production of metabolites that act as potent oxidizing agents, causing oxidation of hemoglobin and subsequent hemolytic anemia. On the other hand, D-methionine, a sulfur-containing amino acid, has been shown to have protective effects against nephrotoxicity and anorexia induced by cisplatin in rats. Furthermore, in pigs, methionine's role as an intracellular antioxidant is highlighted, with supplementation above requirements improving performance and intestinal morphology under heat stress conditions. These findings underscore the importance of monitoring methionine intake in cats to prevent potential adverse effects on red blood cells and overall health.How does the consumption of mango leaf meal affect the blood parameters of broiler chickens?
4 answers
Consumption of mango leaf meal by broiler chickens has varying effects on blood parameters. A study by Omidiwura et al. found that feeding a combination of mango leaf meal and bamboo charcoal to noiler chickens led to significant differences in packed cell volume, hemoglobin counts, white blood cells, and platelets, with some treatments showing higher values. On the other hand, a study by Aka Tanimo et al. revealed that feeding broiler chickens diets containing graded levels of mango leaf meal did not significantly affect parameters like hemoglobin, packed cell volume, and white blood cell count, although differences were observed in red blood cell count and mean corpuscular volume. These findings suggest that the impact of mango leaf meal on blood parameters in broiler chickens can vary depending on the specific study conditions and concentrations used.How do the plant extract restore the level of antioxidant enzymes altered by cadmium in the liver of fish?
5 answers
The plant extracts exhibit hepatoprotective effects by restoring antioxidant enzyme levels altered by cadmium in the liver of fish. Studies on Thunbergia laurifolia, Gynura procumbens, Aerva monsoniae, and Moringa oleifera demonstrate this phenomenon. Thunbergia laurifolia extract increases catalase (CAT) and glutathione peroxidase (GPx) activities while decreasing malondialdehyde (MDA) levels in cell models, protecting against Cd-induced oxidative stress. Gynura procumbens extract enhances superoxide dismutase (SOD) and CAT activities, reducing MDA production in mice liver, counteracting Cd toxicity. Aerva monsoniae extract, along with selenium, restores altered antioxidant enzyme levels in rat liver exposed to Cd, exhibiting protective effects. Moringa oleifera leaf extract decreases AST and ALT levels in Cd-exposed rat livers, indicating improved liver function.What are the current biomarkers used for diagnosing oral syphilis?
5 answers
Currently, there is limited evidence to support the use of specific biomarkers for diagnosing oral syphilis. Research has shown that routine laboratory tests for Treponema pallidum lack the necessary performance characteristics for accurate diagnosis and management of syphilis. However, studies have explored the potential of using oral fluid testing for detecting Treponema pallidum antibodies, showing promising results with high sensitivity levels using rapid syphilis tests. Additionally, a study focusing on serum biomarkers in syphilis patients identified unique peptides corresponding to Treponema pallidum proteins, suggesting the presence of detectable T. pallidum proteins in serum as a potential avenue for developing syphilis diagnostics. Further research is needed to establish reliable and specific biomarkers for diagnosing oral syphilis.How do DPP-4 inhibitors affect the production and absorption of gases in the human intestine?
5 answers
DPP-4 inhibitors impact the production and absorption of gases in the human intestine by regulating DPP-IV activity and peptide cleavage. DPP-4 inhibitors like VLATSGPG and LDKVFR inhibit DPP-IV in intestinal cells, affecting the breakdown of peptides. These inhibitors play a role in glucose metabolism, hunger regulation, and gastrointestinal motility, influencing the absorption of nutrients in the intestine. Studies show that DPP-4 inhibitors, such as sitagliptin and linagliptin, are used to enhance incretin effects in type 2 diabetes patients, impacting metabolic control and potentially improving the quality of life in older individuals. However, the direct effect of DPP-4 inhibitors on gas production or absorption specifically is not explicitly mentioned in the provided contexts.What are the predictors of hspda closure treated with paracetamol?
5 answers
Predictors of successful closure of hemodynamically significant patent ductus arteriosus (hsPDA) treated with paracetamol include gestational age (GA) >26 weeks, birth weight >750g, PDA size ≤0.2cm, and no prior indomethacin use. Additionally, a lower mean platelet volume (MPV) measured prior to treatment initiation was associated with increased risk of hsPDA closure failure with paracetamol. Nonresponders to paracetamol treatment were significantly associated with bronchopulmonary dysplasia (BPD), interventricular hemorrhage (IVH), a PDA to left pulmonary artery ratio >1.0, and ventilation at diagnosis. Moreover, gestational age was identified as an independent predictor of PDA closure in the "first-line" paracetamol treatment group, while the clinical risk index for babies (CRIB) score was predictive of closure failure in the "rescue" treatment group. These factors play crucial roles in determining the efficacy of paracetamol in treating hsPDA.What the patient education should be provided for chronic pancreatitis patients?
5 answers
Patient education for chronic pancreatitis patients should focus on addressing barriers to health literacy and improving understanding of the disease. Visual formats like the Animated Pancreas Patient (APP) educational modules have shown significant impact in educating patients, families, and caregivers. Education should cover topics such as the role and anatomy of the pancreas, foods and beverages to avoid, clinical trials, and different stages of pancreatic cancer. Diagnosis methods like CT, MRCP, and pancreatobiliary endosonography should be explained, along with treatment options including conservative, endoscopic, and surgical interventions. Additionally, psychological therapy like brief interventions can effectively reduce alcohol consumption in alcohol-induced pancreatitis cases, highlighting the importance of addressing underlying causes and lifestyle changes.What does prognosis is impacted when manipulated mean?
5 answers
Prognosis can be significantly affected when mean values are manipulated. For instance, in the context of residual income valuation models, manipulating analyst forecasts through expectations manipulation reduces the usefulness of forecasts in predicting firm value accurately. Similarly, in the field of condition-based prognostics, uncertainty quantification methods like the first-order reliability methods (FORM) can lead to long-term prediction uncertainties, impacting the accuracy of prognostic frameworks. Moreover, in medical contexts like colorectal cancer, alterations in mean platelet volume (MPV) can serve as a prognostic marker, where elevated MPV levels are associated with poorer overall survival rates. Manipulating mean values, whether in financial forecasting, engineering prognostics, or medical prognostication, can have significant implications on the accuracy and reliability of prognostic outcomes.What is the link between lead and iron the body?
5 answers
Lead and iron in the body exhibit a complex relationship. Iron deficiency (ID) and lead exposure have been linked to cognitive and behavioral deficits in children, with evidence suggesting independent associations with cognition and behavior. Studies have shown that iron deficiency can increase lead absorption, potentially leading to body iron overload. In children, blood lead concentrations increase significantly during iron deficient erythropoiesis, but decrease after iron supplementation. Interestingly, in adults, blood lead levels are positively correlated with serum iron and ferritin, indicating a potential interaction between lead exposure and body iron status. Furthermore, genetic factors like the HFE genotype may modify blood lead levels and affect distributions of serum iron and red blood cell indices, suggesting a role in lead toxicity.What are the standard methods used for quality control in full blood count analysis?
5 answers
Standard methods for quality control in full blood count analysis include utilizing delta checks, statistical quality control methods, and Westgard rules. Delta checks are crucial for identifying errors in hematology analyzers. Statistical quality control methods involve monitoring the quality of data through control charts and process control indices. Westgard rules, a set of criteria-based rules, are commonly used to determine the acceptability of analytical runs in medical laboratories. These methods help in detecting errors such as mean shifts and random errors in full blood count analysis, ensuring the accuracy and reliability of the results. By combining these approaches, laboratories can effectively manage and maintain the quality of full blood count analysis processes.What are the factors influence haematological parameters in sports?
5 answers
Haematological parameters in sports can be influenced by various factors. Intense physical performances like football, basketball, marathons, and cycling can significantly impact parameters such as white blood cell count, red blood cell count, hemoglobin, and platelet count. Long-term training and competition periods can lead to fluctuations in parameters like hemoglobin and reticulocytes, with decreases observed during intense training periods throughout the season. Acute training load changes have been shown to affect hemoglobin levels due to short-term plasma volume fluctuations, emphasizing the importance of considering training load when interpreting haematological variations for anti-doping purposes. Additionally, factors like exercise, health status, and the type of sport can also play a role in influencing the biological variation estimates of hematological parameters in athletes.