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How does the presence of potassium hydroxide (KOH) affect the hydrolysis of amino acid salts?

Enzymatic hydrolysis

Reactivity (chemistry)

Intermolecular force

Tetraethylammonium bromide

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The presence of potassium hydroxide (KOH) significantly influences the hydrolysis of amino acid salts. Studies show that the addition of salts like KBr and tetra-n-butylammonium bromide (TBAB) enhances the reaction rate initially, followed by a decrease as their concentration increases . On the other hand, the reactivity trends with NaCl and NaBr differ, leading to a decrease in the reaction rate with their gradual addition . Additionally, the effect of salts on intermolecular interactions between polar/charged amino acids is explored, indicating that salt addition can either stabilize or destabilize these interactions depending on the specific molecules involved . The intricate interplay between salts like KOH and amino acid salts underscores the complexity of hydrolysis processes and their modulation by different salt species.

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Open access•Journal Article Effects of Hydrolysis on Amino Acid Composition Analysis of Proteins Chen Ze 01 Jan 2002-Journal of Analytical Science 1 Citations	Potassium hydroxide (KOH) can influence the completeness of protein hydrolysis for amino acid analysis, impacting factors like temperature, time, and hydrolysis methods, as discussed in the paper.
Journal Article•DOI Kinetic study of the base-catalyzed hydrolysis of novel high-spin hydrophobic Fe(II)-azomethine amino acid chelates: Salt and structure effects on the reactivity Laila H. Abdel-Rahman, Rafat M. El-Khatib, Lobna A. E. Nassr, Ahmed M. Abu-Dief - Show less +3 more 17 Feb 2015-Russian Journal of General Chemistry 1 Citations	The presence of potassium hydroxide (KOH) enhances the hydrolysis rate of amino acid salts, as seen with other alkali metal halides, due to the anionic nature of the transient species.
Journal Article•DOI Salt effects on the reactivity of the base-catalyzed hydrolysis of some novel low-spin hydrophobic Fe(II)-amino acid azomethine chelates Ali M. Shaker, Lobna A. E. Nassr - Show less +1 more 01 Jan 2003-International Journal of Chemical Kinetics 5 Citations	The presence of potassium hydroxide (KOH) enhances the hydrolysis rate of amino acid salts, showing varying reactivity trends based on the type and concentration of the salt.
Open access•Journal Article•DOI Amino acid side chain interactions in the presence of salts. Sergio A. Hassan 24 Nov 2005-Journal of Physical Chemistry B 36 Citations	Not addressed in the paper.
Journal Article•DOI Remarkable Salt Effects in the Highly Enhanced Enantioselective Hydrolysis of Amino Acid Esters with the Active Tripeptide in the Vesicular System Koichi Goto, Chikara Imamura, Shinichi Yamamoto, Yoko Matsumoto, Ryuichi Ueoka - Show less +4 more 05 Nov 1994-Chemistry Letters 6 Citations	Not addressed in the paper.

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