How does the rate constant of hydrolysis of methyl acetate vary with temperature and pH?
Best insight from top research papers
The rate constant of hydrolysis of methyl acetate varies with temperature and pH. At temperatures between 90-110 °C, the neutral hydrolysis of methyl acetate and its catalysis by acetic acid were studied, with rate constants extrapolated to 25 °C . In high-temperature water, the hydrolysis of N-methylacetamide (NMA) follows a first-order reaction with respect to water and NMA, showing pH-dependent behavior with distinct regions of pH sensitivity . Additionally, a new hydrolysis coupling process of methyl acetate utilizes a fixed bed reactor and tower setup to achieve a hydrolysis rate above 97%, emphasizing the importance of catalyst placement and methanol collection for efficient hydrolysis .
Answers from top 5 papers
More filters
| Papers (5) | Insight |
|---|---|
| The rate constant of hydrolysis of methyl acetate varies with temperature and pH, as determined through kinetic data obtained for the reactions involved in the study. | |
| The paper does not address the rate constant of hydrolysis of methyl acetate with temperature and pH. | |
Patent 12 May 2010 4 Citations | Not addressed in the paper. |
35 Citations | The rate constant of N-substituted amide hydrolysis, like N-methylacetamide, is pH-dependent and varies with temperature. It follows first-order kinetics with water in high-temperature conditions. |
14 Citations | The rate constant of methyl acetate hydrolysis increases with temperature and is influenced by pH due to catalysis by acetic acid product. pH affects the reaction kinetics. |
Related Questions
How does temperature affect equilibrum of acid base reaction?5 answersTemperature significantly influences the equilibrium of acid-base reactions. As per studies, increasing temperature can cause shifts in ionization constants of acids and bases, favoring smaller volumes and greater entropies. For instance, in the case of L-glutamine, thermodynamic parameters like pK change with temperature variations, affecting the stepwise dissociation process. Moreover, the behavior of pH indicators like m-Cresol Purple in weakly alkaline solutions at elevated temperatures provides insights into acid-base equilibria in geochemical systems. Additionally, equilibrium constants for the dissociation of various compounds in water have been measured at different temperatures, showcasing the impact of temperature on thermodynamic functions like ΔG°, ΔH°, and ΔS° in acid-base reactions.
How does the presence of a catalyst impact the hydrolysis of methyl acetate?5 answersThe presence of a catalyst significantly influences the hydrolysis of methyl acetate. Different catalyst compositions exhibit varying effects on the reaction. For instance, a catalyst composed of a composite oxide of titanium and silicon, copper, and a metal M oxide additive enhances selectivity towards methyl acetate synthesis, reduces byproduct formation, and ensures stability. In contrast, a catalyst system involving a complex of rhodium carbonyl, acetylmorpholine, and metal, along with various metal stabilizers and iodides as co-catalysts, facilitates a one-step methanol-to-methyl acetate conversion with high activity and stability, simplifying the process and reducing production costs. Additionally, the use of a CuZn–SiO2 catalyst with high dispersion of active species and strong Cu-ZnO interaction leads to improved catalytic activity in methyl acetate hydrogenation.
How does the reaction rate of azidohomoalanine vary under different conditions, such as temperature and pH?5 answersThe reaction rate of azidohomoalanine (Aha) can vary under different conditions such as temperature and pH. Studies have shown that the azido group's vibrational mode is sensitive to changes in electrostatic effects and minor structural variations, as demonstrated by the drastic shift in the IR spectrum upon partial protonation of the N-terminus at different pH levels. Additionally, the incorporation of Aha into proteins using Met-auxotrophic E. coli strains allows for efficient biosynthesis of Aha from inexpensive precursors, providing a platform for site-selective bioorthogonal strategies for noninvasive protein modifications. These findings suggest that the reaction rate of Aha, as indicated by its vibrational frequency in IR spectra, can be influenced by environmental factors like pH and temperature, highlighting its sensitivity as a probe for studying protein structure and dynamics.
What are the reaction rate constants in lipolysis reactions?5 answersThe reaction rate constants in lipolysis reactions vary depending on the specific molecules involved. For instance, in the interaction between ozone and fatty acids, the rate constants were found to depend on factors such as chain length, number of double bonds, and configuration. Additionally, the kinetics of decay of phenoxyl radicals of α-tocopherol and its analog in reactions with fatty acids and phospholipids showed varying rate constants based on the saturation degree of the fatty acids and the type of phospholipids. Furthermore, machine learning algorithms have been proposed to predict reaction rate constants by considering input features and datasets related to activation energies, solvation energies, and reactive force field parameters. These diverse studies highlight the complexity and variability of reaction rate constants in lipolysis reactions.
How does enzyme activity change with temperature?4 answersEnzyme activity changes with temperature in a complex manner. Psychrophilic enzymes, which are adapted to cold temperatures, have different activation parameters compared to enzymes adapted to warmer temperatures. Temperature can have a positive effect on enzymatic catalytic power in the short term, but this effect can be countered over time by enzyme inactivation and reduced substrate affinity. Short-term warming can increase enzymatic catalytic power through accelerated synthesis and microbial turnover, but long-term effects may be mediated by shifts in microbial community composition and growth efficiency. Maintaining a static Km (substrate affinity) with temperature increase ensures high enzyme efficiency within a low and intermediate soil temperature range. Thermal adaptation of enzymes involves changes in both structural and reactive properties, with conformational changes playing a key role in the shift in catalytic activity optimum temperatures. Temperature change can be used as a tool to regulate enzymatic activity, allowing for on-demand enzyme catalysis in various applications.
What are the different stages of the hydrolysis of starch with acid?1 answersThe hydrolysis of starch with acid occurs in multiple stages. In the first stage, the acid preferentially attacks the inner amorphous regions of the starch granules, followed by the outer crystalline areas. This initial stage does not result in any corrosions or fissures in the starch granules. As the hydrolysis progresses, the starch yield decreases, and the average particle size of the starch decreases. Additionally, the crystalline type of starch changes from C-type to A-type. The degree of crystallinity of the starches also increases gradually during the acid hydrolysis process. In the degradation of different types of starch chains, such as waxy maize, maize, high amylose maize, and sago starch chains, two distinct phases of hydrolysis are observed. The first phase involves the degradation of amylose chains with a high degree of polymerization (DP) and amylopectin long intra-cluster branches, while the second phase involves the degradation of amylose chains with a lower DP.