scispace - formally typeset
Search or ask a question

How skeletal muscles grow in albino mice? 


Best insight from top research papers

Skeletal muscle growth in albino mice involves various factors and processes. Studies have shown that platelet-rich plasma (PRP) injections can enhance muscle healing by promoting early activation, proliferation, and differentiation of satellite cells, leading to accelerated myogenesis . Additionally, the differentiation of skeletal muscles, including the glycogen content in different stages, has been observed in detail using electron microscopy, shedding light on the developmental aspects of muscle cells . Furthermore, the role of serotonin in affecting muscle tissues, including smooth and striated muscles, has been highlighted, indicating its impact on muscle function and histological appearance . Stem cell transplantation, specifically adipose tissue-derived stem cells, has shown promise in promoting muscle regeneration and reducing fibrosis in skeletal muscle laceration injuries in female albino rats . These insights collectively contribute to understanding the mechanisms involved in skeletal muscle growth in albino mice.

Answers from top 5 papers

More filters
Papers (5)Insight
Not addressed in the paper.
In albino rats, skeletal muscle regeneration was enhanced by adipose tissue-derived stem cells compared to bone marrow-derived stem cells, showing improved muscle fiber arrangement and reduced fibrosis.
Not addressed in the paper.
Platelet-rich plasma (PRP) injection in injured skeletal muscles of albino rats activates satellite cells, promoting early myotube formation and enhanced muscle regeneration through myogenesis.
The research paper focuses on the electron microscopic study of skeletal muscle development in albino rats, emphasizing glycogen content in differentiative stages of the pectoralis major muscle.

Related Questions

What is the best way to build muscle?4 answersThe most effective way to build muscle involves resistance training combined with adequate protein intake. Research has shown that resistance training is crucial for muscle maintenance and growth. Additionally, consuming dietary supplements like whey protein can support muscle development. A study comparing different training methods found that both circuit training and traditional methods can lead to similar total energy expenditure, but traditional training may utilize the anaerobic pathway more. Furthermore, the timing of protein consumption post-exercise can impact muscle strength gains. Therefore, a combination of structured resistance training, proper protein supplementation, and attention to post-exercise nutrition can be considered the best approach to effectively build muscle mass and strength.
How can i achieve muscle growth?5 answersTo achieve muscle growth, several factors need to be considered. Muscle growth can occur through an increase in muscle cell numbers, an increase in muscle fiber diameter, and an increase in fiber length. Hypertrophy, which involves adding additional myofibrils to increase muscle mass, and adding new sarcomeres to increase fiber length, are the main mechanisms of muscle growth. Muscle growth can be stimulated by exercise, which creates stress and leads to the splitting of myofibrils, increasing the girth of muscle fibers. Additionally, nutrition plays a crucial role in muscle growth, with a nutritionally balanced and calorically adequate diet being required for optimum muscle growth. Regular training, targeted exercises, and the length and intensity of training sessions can induce muscle hypertrophy.
What are the mechanisms by which testosterone affects muscle growth?5 answersTestosterone affects muscle growth through various mechanisms. It enhances insulin sensitivity, decreases fat mass, increases lean mass, and suppresses inflammation. Testosterone activates satellite cells and promotes myonuclear accretion, leading to muscle fiber hypertrophy. It also promotes the commitment of pluripotent precursor cells into myotubes and inhibits adipogenic differentiation. Testosterone increases the expression of fibroblast growth factor (FGF)2, which stimulates satellite cells in skeletal muscle, and decreases the expression of myostatin, a muscle growth suppressor. Additionally, testosterone stimulates protein synthesis, inhibits protein degradation, and improves the reutilization of amino acids, contributing to muscle hypertrophy. These mechanisms collectively explain the anabolic effects of testosterone on muscle growth.
How to grow muscles?5 answersMuscle growth can occur through an increase in muscle cell numbers, an increase in muscle fiber diameter, and an increase in fiber length. Factors such as exercise, nutrition, and the presence of certain molecules can influence muscle growth. Regular training, targeted exercises, and the length and intensity of training sessions can induce muscle hypertrophy. Activation of G protein-coupled receptors, specifically the inhibitor subunit Gα(i2), plays a role in myofiber maturation and growth by stimulating protein synthesis or inhibiting cytokine-dependent protein turnover. Additionally, a method involving alternating pressurizing and movement steps, along with load movements and movement pause steps, can be used to build up muscle. Overall, muscle growth is a complex process influenced by various factors, including exercise, nutrition, and specific signaling pathways.
Is muscle building possible in old age?5 answersMuscle building is possible in old age, although it may be more challenging compared to younger individuals. Age-related impairments in muscle architecture and size, as well as changes in molecular pathways, can limit the ability for muscle growth in older adults. However, interventions such as chronic stretching and eccentric-biased resistance training have shown potential in stimulating muscle growth in old age. Adequate caloric intake, high-quality protein ingestion, and anabolic resistance of aging are important factors to consider for muscle protein synthesis in the elderly. While individual muscle fibers in the elderly can hypertrophy to a similar extent as younger counterparts, the age-related loss of muscle fibers may limit overall muscle hypertrophy in old age. Strength training has been shown to be feasible and beneficial for older individuals, even those with chronic diseases. Structured exercise intervention programs can lead to improvements in muscle strength, flexibility, body composition, and cardiovascular health in overweight/obese individuals across all age groups, including older adults.
What is Albino Rat?2 answersAlbino rats (Rattus norvegicus) are a commonly used animal model in laboratory research. They are derived from naturally occurring albino mutants of the wild Norway rat and have phenotypic differences compared to other genetic backgrounds. Albino rats are characterized by symptoms such as hair loss, dirty hair, itching at the base of the tail, and infestation by ectoparasites. Aberrant pelage color patterns, including albinism, have been reported in some rodent species, although they are relatively rare. Albino specimens have been documented in less than 2% of rodent species, including neotropical species and North American porcupines. Situs inversus totalis, a rare congenital condition where major organs are reversed in position, has also been observed in albino rats. In humans, pagophagia, or ice-eating, is a common symptom of iron-deficiency anemia, and rats made anemic exhibit increased consumption of ice.

See what other people are reading

What are the current advancements in tissue engineering techniques for the aortic artery?
5 answers
Current advancements in tissue engineering for the aortic artery include the utilization of biofabricated scaffolds through 3D printing and bioprinting, the development of tissue-engineered vascular grafts (TEVGs) using scaffold production, genetically modified cells, and nanotechnology-based monitoring, and the exploration of cell sources like skeletal myoblasts for scaffold-free implantable arterial grafts under periodic hydrostatic pressurization (PHP) conditions. These advancements aim to address challenges in creating functional tissues and organs by incorporating blood vessels into engineered tissues. The studies emphasize the importance of regional characterization for aortic assessment, highlighting the structural and biomechanical heterogeneity of aortic tissue along its length and circumference for improved clinical outcomes.
Can increased vitamin D and calcium in nutrition supplements improve bone health and muscle function in the elderly?
10 answers
Increased vitamin D and calcium in nutritional supplements have been shown to have a positive impact on bone health and muscle function in the elderly, although the outcomes can vary based on specific health conditions, supplementation forms, and individual factors. A study demonstrated that a vitamin D, calcium, and leucine-enriched whey protein supplement improved bone mineral density (BMD) and suppressed parathyroid hormone (PTH) in sarcopenic non-malnourished older adults, indicating enhanced bone health. However, a systematic review and meta-analysis found that vitamin D supplementation did not significantly affect markers of muscle function in postmenopausal women, suggesting that the benefits of vitamin D might be more pronounced in bone health than in muscle function for this demographic. Further research highlighted the relationship between higher serum vitamin D levels and better quality of life, including improved muscle strength, in older adults. Supplementation with calcium β-hydroxy-β-methylbutyrate (HMB) and vitamin D3 was found to enhance muscle strength and physical functionality in older adults, even without exercise. This indicates that specific combinations of supplements might be necessary to achieve significant improvements in muscle function. The importance of addressing both sarcopenia and osteoporosis in elderly women through dietary protein, vitamin D, and calcium supplementation, combined with exercise, has been emphasized. Despite the prevalence of vitamin D deficiency in older adults and its association with osteomalacia and osteoporosis, the effectiveness of vitamin D supplementation on BMD and fracture prevention appears inconsistent, with some studies suggesting benefits only when calcium is co-prescribed. Vitamin D supplementation in older patients with inadequate serum levels has been shown to improve muscular strength but not muscle mass or performance. The role of vitamin D in muscle function remains under debate, with some studies questioning the direct action of vitamin D on muscle due to low expression of the vitamin D receptor (VDR) in adult human muscle. Nonetheless, vitamin D's importance to muscle health is supported by its association with reduced musculoskeletal pain and sarcopenia. Finally, a meta-analysis concluded that calcium supplementation with or without vitamin D does not increase coronary heart disease or all-cause mortality risk in elderly women, suggesting the safety of these supplements in this population. In summary, while increased vitamin D and calcium in nutritional supplements can improve bone health and may enhance muscle function in the elderly, the effectiveness and mechanisms may vary, highlighting the need for personalized supplementation strategies.
What is the orgin of milk fat in ruminants?
5 answers
The origin of milk fat in ruminants is multifaceted. A significant portion of milk fatty acids in ruminants is derived from de novo synthesis within the mammary gland, utilizing precursors like acetate and butyrate from ruminal fermentation. Additionally, long-chain fatty acids are absorbed from circulating lipoproteins and nonesterified fatty acids, originating from dietary lipid absorption and body fat mobilization. The rumen plays a crucial role in the composition of milk fat, influencing the fatty acid profile through biohydrogenation of dietary unsaturated fatty acids. This complex interplay between mammary lipogenesis, rumen lipid metabolism, and dietary factors contributes to the diverse composition of milk fat in ruminants, making it a vital component of their diet and human consumption.
What ate the particular muscle group develop using dumbbells ni gym?
5 answers
Dumbbells in the gym are particularly effective for developing various muscle groups. Specifically, dumbbells are beneficial for fortifying muscles like the biceps, triceps, and back muscles. Additionally, research has shown that dumbbell exercises, such as dumbbell curls, are crucial for strengthening the upper extremities, especially the biceps brachii. Moreover, studies have highlighted the significance of dumbbell exercises in enhancing muscle endurance, which is essential for athletes, by positively affecting muscular endurance when combined with weightlifting movements. Furthermore, electromyographic studies have demonstrated high levels of muscle activity in shoulder muscles like the deltoid and pectoralis major during dumbbell exercises, supporting their inclusion in fitness programs for these muscle groups.
What is red bean?
4 answers
Red bean, scientifically known as Phaseolus vulgaris L., is a versatile legume with various applications in food products. It is rich in nutrients and can be processed into items like tempeh chips and biscuits, offering nutritional benefits. Red bean also exhibits anti-inflammatory and antioxidant properties, making it valuable in combating oxidative damage and inflammation. Moreover, red bean extract has shown potential in inhibiting muscle atrophy by enhancing muscle strength and protein synthesis. Additionally, red bean can be creatively combined with coffee to create a unique beverage that retains the aroma of coffee and the smoothness of red beans, catering to individuals of all ages. Overall, red bean is a multifaceted ingredient with diverse culinary, nutritional, and health-promoting attributes.
What are the top 10 vitamin B complex rich foods that provide the most health benefits?
5 answers
Vitamin B complex-rich foods that offer significant health benefits include a variety of sources. Legumes, whole grains, potatoes, bananas, chili peppers, tempeh, nutritional yeast, brewer’s yeast, and molasses are excellent sources of B vitamins. Additionally, meat, eggs, and dairy products like butter, yogurt, and cheese from mammals such as buffaloes, cattle, goats, sheep, and camels are rich in B vitamins. These foods provide essential B vitamins like thiamine (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), pyridoxine (B6), biotin (B7), folate (B9), and cobalamin (B12). Consuming a varied diet that includes these vitamin B complex-rich foods can help maintain optimal energy levels, support brain function, and promote overall cell metabolism, thereby contributing to a healthy lifestyle.
How do Lysophosphatidylcholines affect obesity?
5 answers
Lysophosphatidylcholines (LPCs) play a significant role in obesity-related metabolic changes. Studies show that obesity is linked to alterations in the lipidomic profile, with LPCs being highlighted as potential biomarkers of obesity. In individuals with obesity, there is an increase in lysophospholipids (lyso-PLs) and lysophosphatidylcholine acyltransferase 3 (LPCAT3) expression, impacting skeletal muscle insulin sensitivity. Furthermore, a strong correlation exists between lysophosphatidylcholine levels and muscle contractile force, with LPCAT3 influencing muscle strength and myopathy development in obesity. Additionally, specific LPC species like LPC (17:0) have been found to reduce blood glucose, alleviate insulin resistance, and activate G protein-coupled receptors, suggesting a protective role against hyperglycemia and insulin resistance in obesity-related conditions.
How muscle growth occurs?
5 answers
Muscle growth occurs through a combination of processes involving muscle fiber development, hypertrophy, and protein synthesis. Initially, muscle fibers are established in the embryo and grow through the formation of primary and secondary fibers, controlled by factors like myostatin. Myogenesis, the process from mesenchymal cells to mature muscle fibers, is influenced by various factors like genotypes, nutrition, and environmental treatments, impacting muscle fiber number and performance traits. Hormones, growth factors, and mechanical signals play roles in inducing muscle hypertrophy, regulating protein synthesis and gene activation. Muscle growth involves hypertrophy of existing fibers through myofibril addition and new sarcomeres, with nutrition playing a crucial role in protein deposition and overall growth. Muscle growth is most rapid in the perinatal period, driven by nutrient availability and signaling pathways, with critical windows in early development for optimal growth.
What is kreatin supplementation effect on muscle mass?
5 answers
Creatine supplementation has been extensively studied for its effects on muscle mass. Research indicates that creatine supplementation can lead to increased muscle mass. Studies have shown that creatine supplementation, when combined with resistance training, can result in significant gains in muscle mass. Additionally, creatine has been linked to enhancing muscle growth and hypertrophy through various mechanisms, such as acting as an anabolic stimulus for protein synthesis pathways and affecting myogenic processes. A study on male bodybuilders revealed that creatine supplementation significantly augmented body mass and muscle circumferences, particularly in the chest, biceps, and thigh areas. Furthermore, in handball players, short-term creatine supplementation led to a significant increase in fat-free mass, indicating a positive impact on muscle mass.
What is the role of dopamine in motivation in mice?
5 answers
Dopamine plays a crucial role in motivation in mice by modulating various aspects of behavior. Studies have shown that dopamine release in the nucleus accumbens (NAc) correlates with motivation towards conspecifics during social behaviors. Additionally, specialized dopamine neurons in the hypothalamus control mating behaviors in male mice, with dopamine transients regulating mating drive and satiety. Furthermore, dopamine is implicated in regulating adaptive feeding behavior without altering energy balance, enhancing local meal motivation in mice. DAT mutant mice exhibit hyperlocomotive behavior and reduced anxiety levels, indicating complex developmental stage-dependent effects of dopamine signaling on cognitive and emotional behaviors. Overall, dopamine's involvement in motivation encompasses social interactions, mating behaviors, feeding behavior, locomotion, and emotional responses in mice.
The extract of purple cactus is applied in meat or any meat products ?
5 answers
The extract of purple cactus, specifically Opuntia ficus-indica, is indeed applied in meat and meat products for various purposes. It is utilized in processes such as aging meat to enhance taste and remove foul smells, as well as in seasoning compositions for roasted meats to improve quality, eliminate meaty odors, and enhance flavor, ultimately increasing appetite. Additionally, the cactus fruit extract is rich in red and purple pigments, which can be used for dyeing, anti-oxidation, and bacteria inhibition in food products. The antioxidant properties of the purple cactus extract have been evaluated, showing significant antioxidant activity, making it suitable for applications in whipped cream and other food products. Therefore, the purple cactus extract finds versatile applications in the meat industry, contributing to both flavor enhancement and health benefits.