How to prevent giant cell arteritis?
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Preventing giant cell arteritis (GCA) involves early diagnosis and prompt treatment to avoid vision loss and disease progression. Glucocorticoids are the mainstay of treatment, significantly reducing ischemic complications and relieving symptoms . However, due to the adverse effects of long-term corticosteroid use, glucocorticoid-sparing treatments like methotrexate and tocilizumab may be necessary . Recurrences during corticosteroid tapering are common, necessitating careful monitoring and potential escalation of treatment . Adjunctive therapies such as tocilizumab, methotrexate, aspirin, angiotensin receptor blockers, and statins show promise in managing relapses and reducing corticosteroid-related complications . Preventive measures to mitigate cardiovascular, infectious, and osteoporosis risks should also be included in the management of GCA patients .
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11 Citations | Early diagnosis, prompt treatment with high-dose corticosteroids, regular monitoring with ESR and CRP, and considering adjunctive therapies like tocilizumab and methotrexate can help prevent complications of giant cell arteritis. |
| Preventive measures for giant cell arteritis include reducing cardiovascular, infectious, and osteoporosis risks. Treatment primarily involves glucocorticoids, with potential glucocorticoid-sparing options like methotrexate and tocilizumab. | |
| Human Monocyte-derived Suppressive Cells (HuMoSC) or their supernatant show promise in decreasing vascular inflammation and remodeling in Giant Cell Arteritis, potentially offering a novel therapeutic approach. | |
| Prevent giant cell arteritis by utilizing glucocorticoids as the mainstay treatment, considering immunosuppressive therapies like tocilizumab, and exploring emerging targeted therapies for optimal management. |
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