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Role of Green Metallic nanoparticles for periodontal disease?

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Green metallic nanoparticles synthesized using plants, extracts, algae, fungi, bacteria, and biomolecules offer a promising and eco-friendly approach for various applications, including periodontal disease treatment. These nanoparticles can be synthesized quickly, at low cost, and without the use of toxic chemicals or high-energy consumption . The synthesis mechanism of metal nanoparticles by living organisms is not fully understood, but bioreduction processes involving nitrate reductase have been identified as key steps . The physical and chemical properties of nanoparticles, such as morphology, zeta potential, and composition of capping agents, can be controlled during the biosynthesis process . Furthermore, the use of metallic nanoparticles has shown potential for enhancing bone formation at the implant/biomaterial and bone tissue interface, which could be beneficial for periodontal disease management .

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Open access•Book•DOI Novel Nano-Engineered Biomaterials for Bone Tissue Engineering 24 Mar 2022	The provided paper does not mention the role of green metallic nanoparticles for periodontal disease. The paper is about novel nano-engineered biomaterials for bone tissue engineering.
Open access•Book•DOI Optical Properties of Metallic Nanoparticles Andreas Trügler 01 Jan 2016 58 Citations	The provided paper does not discuss the role of green metallic nanoparticles for periodontal disease.
Open access•Book Nanomaterials : toxicity, health and environmental issues Challa S. S. R. Kumar 01 Jan 2006 94 Citations	The provided paper does not mention the role of green metallic nanoparticles for periodontal disease.
Book•DOI Nanotechnology Applied To Pharmaceutical Technology Mahendra Rai, Carolina Alves dos Santos - Show less +1 more 01 Jan 2017 14 Citations	The provided paper does not mention the role of green metallic nanoparticles for periodontal disease.
Open access•Book Metallic Nanocrystallites and their Interaction with Microbial Systems Anil K. Suresh 14 Mar 2012 16 Citations	The provided paper does not mention the role of green metallic nanoparticles for periodontal disease. The paper provides an overview of nanotechnology and its applications in various fields, including biotechnology and biomedicine.

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Can local drug delivery systems using nanoparticles based gels improve the efficacy of periodontitis treatments?5 answersLocal drug delivery systems utilizing nanoparticles-based gels have shown promise in enhancing the efficacy of periodontitis treatments. Nanobioactive protective films created by NBF gel have demonstrated increased absorption and improved clinical effectiveness in reducing periodontal parameters. Additionally, copper nanoparticles gel has exhibited antimicrobial properties against periodontal pathogens, with promising results in in-vivo analysis as a local drug delivery agent. The use of locally administered metronidazole gel and tetracycline fibers alongside scaling and root planing has shown improved outcomes in reducing periodontal pocket depth. These findings highlight the potential of nanoparticle-based gels in enhancing the therapeutic outcomes of periodontitis treatments through targeted drug delivery systems.

Can local drug delivery systems using zinc oxide nanoparticles based gels improve the efficacy of periodontitis treatments?5 answersLocal drug delivery systems utilizing nanoparticles, such as copper nanoparticles and nanobioactive protective films, have shown promise in enhancing the efficacy of periodontitis treatments. Studies have highlighted the advantages of these systems, including improved clinical effectiveness, sustained drug release, and antibacterial properties. Additionally, research has demonstrated that combining systemic antimicrobial agents with non-surgical periodontal treatments can effectively eliminate microorganisms in periodontitis cases. Furthermore, the use of controlled local drug delivery approaches, like zinc oxide nanoparticles based gels, offers targeted therapy, reduced side effects, and improved patient compliance, making them a favorable option for periodontal treatment. Therefore, incorporating zinc oxide nanoparticles in local drug delivery systems could potentially enhance the efficacy of periodontitis treatments by leveraging the benefits observed in existing nanoparticle-based therapies.

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