Search or ask a question

What are the Pros and Cons of Ashwagandha Supplementation?

Context (archaeology)

Withania somnifera

Best insight from top research papers

Ashwagandha supplementation offers various benefits such as stress reduction, improved sleep quality, enhanced mental clarity, and increased energy levels . It also shows potential in managing obesity by lowering cortisol levels, inhibiting fat accumulation, and impacting genes involved in fat tissue accumulation . However, there are reported cases of liver damage associated with ashwagandha use, indicating a potential risk of hepatotoxicity . Additionally, while Withaferin A, a compound found in Ashwagandha, has shown therapeutic potential in various health conditions, further research is needed to fully understand its mechanisms and ensure safety . Therefore, while Ashwagandha can be beneficial for stress relief, sleep improvement, and overall well-being, caution should be exercised regarding its potential side effects, particularly related to liver health.

Answers from top 4 papers

PDF

Open Access

More filters

Papers (4)	Insight
Open access•Journal Article•DOI Ashwagandha (Withania somnifera) - influence on sleep: review Przemysław Jędruszczak, Sylwia Zdun, Klaudia Walczak, Zuzanna Wesołowska, Weronika Gaweł - Show less +4 more 20 Jan 2023-Quality in Sport	Pros of Ashwagandha supplementation include improved sleep quality and duration, reduced oxidative stress during sleep deprivation, and potential treatment for restless legs syndrome. Cons were not addressed in the paper.
Journal Article•DOI The Perceived Impact of Ashwagandha on Stress, Sleep Quality, Energy, and Mental Clarity for College Students: Qualitative Analysis of a Double-Blind Randomized Control Trial. Cynthia Baker, Jessica Brooke Kirby, Jack O'Connor, Keston G. Lindsay, Andrea M. Hutchins, Margaret Sharon Harris - Show less +5 more 18 Aug 2022-Journal of Medicinal Food 3 Citations	Ashwagandha supplementation for college students showed increased energy, mental clarity, and sleep quality. However, potential cons were not addressed in the study.
Journal Article•DOI Revisiting the Multifaceted Therapeutic Potential of Withaferin A (WA), a Novel Steroidal Lactone, W-ferinAmax (Ashwagandha), from Withania Somnifera (L) Dunal. Pawan Kumar, S. Banik, Apurva Goel, Sanjoy Chakraborty, Manashi Bagchi, Debasis Bagchi - Show less +5 more 06 Jul 2023-Journal of the American Nutrition Association	Pros of Ashwagandha supplementation include versatile therapeutic benefits for various ailments. Cons may involve potential safety and toxicity concerns, which require further research for clarification.
Open access•Journal Article•DOI Benefits of Withania somnifera (Ashwagandha) supplementation in obesity 29 May 2023-Journal of Education, Health and Sport	Pros of Ashwagandha Supplementation: Improved insulin sensitivity, reduced cortisol levels, anti-adipogenic effects. Cons: Need for further research in obesity therapy.

My columns

Related Questions

What are the health benefits of Ashwaganda?4 answersAshwagandha, also known as Withania somnifera or winter cherry, has been found to have numerous health benefits. It is commonly used in traditional Ayurvedic medicine and has been shown to have sedative, anti-stress, immunomodulatory, and anti-cancer effects. Ashwagandha has also been found to improve insulin sensitivity, increase endurance, and inhibit fat accumulation. It has been shown to have adaptogenic potential and can be beneficial in the context of obesity and obesity-related diseases. Additionally, Ashwagandha has neuroprotective, anti-inflammatory, antimicrobial, cardioprotective, and anti-diabetic properties. It has been found to enhance adaptogenesis, improve sleep quality, and benefit certain neuropsychiatric conditions. Furthermore, Ashwagandha has been found to have antioxidant and anti-inflammatory effects, and it may also improve cognitive functioning and exercise capacity. Overall, Ashwagandha shows promise as a natural remedy for various health concerns, but further research is needed to fully understand its potential uses.

What are the effects of Ashwagandha on the body?5 answersAshwagandha has a wide range of positive effects on the body. It has been found to have sedative, anti-stress, immunomodulatory, and anti-cancer effects. Ashwagandha supplementation has been shown to improve muscle mass, strength, and cardiorespiratory endurance in individuals engaging in resistance training. It has also been found to improve fertility in both men and women and enhance libido. Additionally, Ashwagandha has antioxidant properties and can help manage chronic ailments such as tuberculosis and diabetes mellitus associated with stress, anxiety, insomnia, and loss of energy. It has been used as an adjuvant in the treatment of tuberculosis and diabetes mellitus. Ashwagandha has been shown to increase sperm concentration and motility, decrease stress levels, and improve overall sperm quality. Overall, Ashwagandha has the potential to improve various aspects of health and well-being.

Does Ashwagandha supplementation improve sleep quality in patients with insomnia?4 answersAshwagandha supplementation has shown potential in improving sleep quality in patients with insomnia. Studies have reported that Ashwagandha root extract can improve sleep parameters in both insomniacs and healthy individuals. It has been found to increase total sleep duration and decrease time to sleep onset in animal models. Furthermore, Ashwagandha has been shown to have a positive effect on sleep quality and length, as well as reducing oxidative stress under conditions of sleep deprivation. The improvement in sleep quality has been attributed to Ashwagandha's effects on GABA-nergic transmission and the chemical triethylene glycol. However, it is important to note that further research on a larger scale is needed to fully understand the potential benefits of Ashwagandha supplementation for improving sleep quality in patients with insomnia.

What does the research say about ashwaganda health benefits?4 answersAshwagandha has been studied for its health benefits in various conditions. Research suggests that it has positive effects on stress and anxiety symptoms. It has also been found to have sedative, anti-stress, immunomodulatory, and anti-cancer effects. Ashwagandha may improve insulin sensitivity, increase endurance, and inhibit fat accumulation. It has been used in traditional medicine for its therapeutic properties, including anti-inflammatory, anti-tumour, and anti-ageing effects. Additionally, Ashwagandha has been shown to boost the immune system, fight inflammation, increase memory power, and improve overall health and wellness. Studies have also indicated that it may have potential benefits in the treatment of depression, withanolides and alkaloids being the main components responsible for its antidepressant effects. However, further research is needed to fully understand the mechanisms of action and to determine the optimal dosage and duration of treatment.

What are the effects of ashwagandha supplementation on cortisol levels?4 answersAshwagandha supplementation has been found to have an effect on cortisol levels. One study found that daily supplementation of ashwagandha for ten weeks resulted in a minimal response to an intramuscular injection of Synacthen, indicating adrenal hypofunction. However, this effect was reversible after a two-week break from supplementation. Another study showed that both 225 mg/d and 400 mg/d doses of ashwagandha led to reductions in cortisol levels over time, with the 225 mg/d group showing significant reductions from Day 0 to Day 15 to Day 30. These findings suggest that ashwagandha supplementation can decrease circulating cortisol levels.

Is ashwaghanda a legit supplement?5 answersAshwagandha is a legitimate supplement that is widely used in the ayurvedic system. It is known for its various bio-physiological properties and is used as a tonic for the nerves, memory enhancer, antirheumatic item, aphrodisiac, and adaptogen. However, it is important to note that the purity and safety of ashwagandha supplements can vary. Adulteration is a common issue with these supplements, and the content of physiologically active substances such as withanolides, saponins, and alkaloids can vary among different brands. Therefore, it is crucial to choose ashwagandha supplements from reputable brands and ensure that they have been tested for quality and purity.

See what other people are reading

Does the consumption of specific nutrients at certain times affect the recovery and muscle growth of wrestlers?

Consumption of specific nutrients at certain times can indeed impact the recovery and muscle growth of wrestlers. Nutrient timing plays a crucial role in promoting recovery, training adaptations, and muscle regeneration. For judo athletes, a balanced intake of macronutrients is essential, with carbohydrates comprising 55-60%, fats 25-30%, and proteins 15-20% of their diet. Additionally, the timing of protein intake around exercise sessions can enhance recovery and lean body mass gains, especially with essential amino acids and leucine supplements. Furthermore, incorporating efficacious micronutrients and ingredients, such as vitamin D, omega-3 fatty acids, creatine, and antioxidants, can support recovery during the competitive season for team sport athletes, including wrestlers. Thus, strategic nutrient consumption at specific times can positively influence the recovery and muscle growth of wrestlers.How does the use of big data in journalism affect the credibility and accuracy of news reporting?

The utilization of big data in journalism significantly impacts the credibility and accuracy of news reporting. Data journalists possess unique skills to find, gather, and use data effectively, enhancing the quality of stories. Big data enables the creation of visually coherent and scientifically sound content, improving the objectivity and depth of reporting. By analyzing data sets and establishing correlations, journalists can provide quantitative evidence for their theses, increasing audience trust and loyalty to publications. Furthermore, the adoption of big data in journalism has revolutionized news production and distribution processes, introducing new tools and technologies that enhance the overall practice of journalism. Overall, the integration of big data in journalism not only enhances the credibility of news reporting but also ensures greater accuracy and reliability in the information presented to the audience.How trauma leads to child social withdrawal in school?

Trauma in children can lead to social withdrawal in school due to the complex effects it has on their emotional and psychological well-being. Children exposed to trauma may exhibit behaviors such as shyness, unsociability, and social avoidance, which are different subtypes of social withdrawal with unique underlying emotional and motivational factors. Maternal trauma-related psychopathology, such as posttraumatic stress disorder (PTSD) and major depressive disorder (MDD), can impact infant social withdrawal, highlighting the intergenerational transmission of trauma-related symptoms. Additionally, traumatic experiences can disrupt a child's physical and psychological capacity to cope, leading to pervasive disruptions in intrapersonal and interpersonal development, affecting their academic performance, self-value, and social development in school. These factors collectively contribute to how trauma can manifest as social withdrawal in children within the school environment.1.What are the key strategies used for integrating biodiversity in Large urban infrastucture?

Key strategies for integrating biodiversity in large urban infrastructure include prioritizing urban biodiversity in decision-making, defining operational standards for biodiversity application, identifying robust metrics, ensuring actions contribute to socioeconomic goals, connecting drivers of biodiversity loss across boundaries, and synergizing biodiversity conservation with human needs. Additionally, utilizing green infrastructure (GI) can serve as a vessel for promoting biodiversity, enhancing ecosystem services, and improving human well-being in cities. Implementing Nature-Based Solutions (NBS) within a GI framework can maximize ecosystem benefits, protect biodiversity, and enhance urban resilience. By adopting a socio-ecological systems approach, cities can address governance challenges, understand contextual factors shaping relationships between UGI and biodiversity, and design UGI systems effectively to support global conservation goals while benefiting urban residents.How do large language models compare to classic ML in sentiment analysis?

Large language models (LLMs) like ChatGPT show satisfactory performance in simpler sentiment analysis tasks but struggle with more complex tasks requiring deeper understanding. In financial sentiment analysis, LLMs face challenges in interpreting numerical values and financial context, limiting their effectiveness. However, a study using semi-supervised learning with LLMs for market sentiment analysis on social media found that with proper training methods, LLMs can perform on par with existing supervised models, showcasing their potential for skill-intensive tasks. Overall, while LLMs excel in certain aspects of sentiment analysis and outperform small language models in few-shot learning scenarios, they may lag behind classic machine learning models in tasks requiring specialized domain knowledge or structured sentiment information.I need a definition of sucess factors in the context of change management?

Success factors in the context of change management refer to key elements that contribute to the effective planning and implementation of organizational changes. These factors include aspects such as communication, creating a vision for change, active participation of all individuals, and commitment from top management. Additionally, involving stakeholders, implementing change agents, maintaining clear communication at different management levels, addressing problems transparently, and adhering to defined timelines are crucial success factors in change management within the medical technology sector. Success in change management also hinges on effective communication strategies that create transparency, resolve conflicts, and motivate individuals throughout the change process. Furthermore, maintaining motivation, ensuring goal orientation, and appointing capable individuals to project roles are essential success factors for sustainable change processes.What strategies can be used to structure construction contracts to effectively manage supply chain disruptions caused by unforeseen circumstances?

To effectively manage supply chain disruptions in construction caused by unforeseen circumstances, strategies such as adopting suitable contract types, implementing risk management frameworks, and enhancing collaboration among stakeholders are crucial. Contract types should be carefully matched to stakeholder profiles to mitigate opportunism and improve transparency. Additionally, a proactive and systematic approach to disruption claim management, initiated early in the contract development phase, can help in compensating losses and reducing prolonged dispute resolution processes. Medium-sized firms may opt for a wait-and-see strategy, while larger organizations can deploy resources to reduce risks caused by disruptions. Overall, a combination of strategic fit with the external environment, risk assessment, contract optimization, and stakeholder collaboration is essential for effectively structuring construction contracts to manage supply chain disruptions.How fruits and vegetables reduce risk of cardiovascular disease?

Consuming fruits and vegetables has been consistently linked to a reduced risk of cardiovascular disease (CVD) through various mechanisms. Vegetables, rich in bioactive compounds, offer cardio-protective effects such as antioxidant, anti-inflammatory, and blood pressure regulation. Increasing fruit and vegetable intake by one cup per day could prevent incident CVD and CVD-related deaths, especially in individuals with hypertension, showcasing significant population health benefits. Antioxidants present in fruits, vegetables, nuts, and cereals play a crucial role in reducing CVD risk, with polyphenols, anthocyanins, and other bioactive compounds improving lipid profiles, reducing blood pressure, and mitigating inflammation. Large-scale studies have shown that higher fruit and vegetable consumption is associated with a lower risk of CVD and all-cause mortality, emphasizing the importance of incorporating these foods into daily diets for CVD prevention.Why do student procrastinate?

Students procrastinate due to various internal and external factors. Internal factors include laziness, fear of failure, perfectionism, poor study habits, preference for exciting activities, distractions, lack of clarity, and poor communication with teachers. External factors, such as parenting styles, can also contribute to academic procrastination. The pressure to meet high academic standards while juggling other responsibilities like work or extracurricular activities can lead students to delay tasks until the last minute. Procrastination can have both positive and negative impacts, with last-minute rushes sometimes boosting productivity and creativity, but also potentially hindering learning and productivity in the long run. Online learning environments can exacerbate procrastination due to increased student autonomy in managing academic tasks.Does the comics images and storyline have motivated learners in learning the effect temperature to the speed of sound?

The implementation of comic media in learning has shown a positive correlation with student motivation. Comics, with their visual appeal and engaging storyline, have been found to foster student interest and increase motivation during the learning process. Research indicates that the use of comics as a learning medium can significantly enhance student motivation and participation, leading to improved learning achievement. Additionally, comics have been shown to effectively convey concepts and engage students, particularly those with lower initial content knowledge, resulting in improved attitudes towards the subject matter. Therefore, utilizing comics with images and engaging storylines can indeed motivate learners in understanding the effect of temperature on the speed of sound by enhancing engagement and interest in the topic.How has globalization affected the way businesses operate?

Globalization has transformed the landscape of international business by expanding markets beyond borders, creating growth opportunities, and increasing competition. Companies have evolved structurally to operate globally, surpassing national boundaries, while also raising concerns about governmental fulfillment of human rights obligations and the inadequacy of international law in regulating multinational corporations. Technological advancements have further intensified global competition, prompting businesses to seek opportunities beyond local markets and adapt to changes in cultural practices. The shift towards an information society due to globalization and digital technologies has significantly impacted internal trade, leading to a rise in electronic commerce and the exploration of new distribution channels and economic opportunities. Overall, globalization necessitates businesses to adapt strategies, understand local markets, invest in technology, and remain flexible to thrive in the dynamic global business environment.