What factors influence the synthesis of staphylococcal enterotoxin?
Best insight from top research papers
Factors that influence the synthesis of staphylococcal enterotoxin include temperature, pH, and the presence of certain sugars. Different temperatures and pH levels have been found to affect the production of enterotoxins by Staphylococcus aureus . Optimum conditions for enterotoxin production were observed at 37°C and pH 6.5 . The production of enterotoxins was also influenced by the presence of sugars such as glucose, 2-deoxyglucose, and α-methylglucose, which inhibited enterotoxin synthesis . The inhibitory effects of these sugars on enterotoxin synthesis may be related to a mechanism similar to catabolite repression . Additionally, the initial numbers of lactic acid bacteria present in the environment can also affect the growth and ability of Staphylococcus aureus to produce enterotoxins . Overall, factors such as temperature, pH, and the presence of specific sugars and bacteria can influence the synthesis of staphylococcal enterotoxin.
Answers from top 5 papers
More filters
| Papers (5) | Insight |
|---|---|
6 Citations | The paper suggests that glucose and its analogs, such as 2-deoxyglucose and α-methylglucose, inhibit the synthesis of staphylococcal enterotoxin A (SEA). The inhibition of SEA synthesis may be regulated by a mechanism similar to catabolite repression. |
Open access•Journal Article 3 Citations | The paper mentions that factors such as pH, temperature, and the presence of inductors and repressors can influence the synthesis of staphylococcal enterotoxin. |
| The paper does not provide information about the factors that influence the synthesis of staphylococcal enterotoxin. | |
14 Citations | The factors that influence the synthesis of staphylococcal enterotoxin (SEC) include temperature, pH, growth phase, and growth medium. |
08 Mar 2017 4 Citations | The paper does not provide specific information on the factors that influence the synthesis of staphylococcal enterotoxin. |
Related Questions
Relation between heat treatment and enterotoxin production?5 answersHeat treatment has been found to have varying effects on enterotoxin production. In the case of Enterotoxigenic Escherichia coli (ETEC), heat-stable enterotoxin (ST) production was suppressed by iron restriction, while magnesium limitation increased the production of colonization factor (CF) CFA/I. Simultaneous exposure to heat-labile toxin (LT) and ST in ETEC strains resulted in increased water movement into the intestinal lumen and elevated levels of intracellular cyclic GMP (cGMP). High pressure treatment also had an impact on bacterial enterotoxins, with pressurization increasing inactivation observed by heat treatment. Additionally, heat treatment prior to incubation enhanced enterotoxin production in some strains of Clostridium perfringens. These findings suggest that heat treatment can modulate enterotoxin production, with the specific effects depending on the bacterial strain and the presence of other factors such as magnesium and iron availability.
Relation between heat treatment and STAPHYLOCOCCAL enterotoxin production?4 answersHeat treatment has been found to have an impact on the production of Staphylococcal enterotoxins (SEs). Staphylococcal food poisoning (SFP) is caused by the consumption of foods containing preformed SEs, which are heat stable and can withstand high temperatures. However, the production of SEs is influenced by various factors including temperature and nutrients. Studies have shown that the incubation temperature affects the production of SEA, with little relationship found between the maximal SEA concentrations and incubation temperature. Additionally, differential scanning calorimetry (DSC) studies have shown that the thermal stabilities of SEs SEA, SEB, and SEH are influenced by pH and ionic strength, which are typical factors in food. Therefore, while heat treatment may not completely prevent the production of SEs, it can impact their stability and potential renaturation after heat treatments.
What are the characteristics of a new-type staphylococcal enterotoxin?5 answersA newly identified staphylococcal enterotoxin Q (SEQ) has been found to exhibit remarkable stability to heat treatment and digestive enzyme degradation. It also has significant superantigenic and emetic activities, making it a high-risk toxin in food poisoning. Another study found that a nonclassical staphylococcal enterotoxin (SEQ) had stability to heat treatment and enzyme degradation, but some strains carried genes that coded for a nonfunctional protein. Staphylococcal enterotoxin B (SEB) produced by methicillin-resistant Staphylococcus aureus is a major cause of pathology after a staphylococcal infection. An anti-SEB human monoclonal antibody, M0313, has been found to accurately recognize and bind to SEB, effectively inhibiting its activity and neutralizing its toxicity in mice. The production of staphylococcal enterotoxin type A (SEA) in shaking culture was found to be higher than in stationary culture, but the productivity, or maximum amount produced by one cell, was lower in shaking cultures. Different strains showed different patterns of SEA production, suggesting strain-specific characteristics.
What are the common symptoms of Staphylococcus enterotoxin A infection?5 answersStaphylococcus enterotoxin A (SEA) infection commonly presents with symptoms such as vomiting, diarrhea, nausea, and abdominal pain.
How many types of enterotoxin are produced by S. aureus?5 answersStaphylococcus aureus produces multiple types of enterotoxins. The enterotoxin gene content in wild boar S. aureus isolates included seb, sec, see, and seh genes. Enterotoxin type A was found in S. aureus isolates from various sources, including pathogenic isolates, soil, food, tape water, and nasal swabs. Wild-type sea-positive S. aureus isolates were found to produce enterotoxin A, as well as other enterotoxin gene profiles such as sec, seb, sed, and sea+seb+sec. Staphylococcus aureus isolated from human infections in Zabol was found to produce enterotoxin E. Additionally, new-type enterotoxin genes, including SEj, SEl, SEq, SEm, and SEr, were identified in S. aureus isolates from different origins. Therefore, S. aureus is capable of producing multiple types of enterotoxins, including enterotoxin A, enterotoxin E, and other newly identified enterotoxin genes.
What does staphylococcal enterotoxin ?5 answersStaphylococcal enterotoxins are a group of secreted virulence factors produced by Staphylococcus aureus that have potent superantigenic activity and can cause disruptions in adaptive immunity. They are classified as superantigens due to their ability to stimulate the immune system, resulting in T cell activation and cytokine production. Staphylococcal enterotoxins can be separated into two groups: the classical enterotoxins (SEA-SEE) and the newer enterotoxins (SEG-SElY). These enterotoxins are responsible for a wide range of diseases in humans and animals, including toxic shock syndrome, pneumonia, sepsis-related infections, and food poisoning outbreaks. They are frequently found in S. aureus isolates, with the most common enterotoxin gene being sec, followed by sea and see. Multiple enterotoxin genes combinations are also common in S. aureus strains, indicating their strong virulent potential.