What gives the agarose gel a maze like structure?
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The maze-like structure of agarose gel is attributed to the formation of a fibrous network composed of aggregated double helices of agarose. This network exhibits conformational variations depending on the agarose concentration, with fiber diameters generally increasing as concentrations rise. Additionally, at lower agarose concentrations, the network displays protuberances or cul-de-sacs, contributing to the intricate maze-like appearance of the gel. The distribution of void volumes within agarose gels, as revealed by small angle neutron scattering (SANS), aligns with a random network of cylindrical fibers described by the Ogston model. These structural characteristics, along with the impact of agarose concentration and conformation on pore size and distribution, collectively contribute to the maze-like spatial arrangement observed in agarose gels.
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| Papers (5) | Insight |
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| The agarose gel's maze-like structure is attributed to a random network of cylindrical fibers, as revealed by small angle neutron scattering (SANS) measurements in the study. | |
29 Citations | The aggregated double helices of agarose form a fibrous network, creating a maze-like structure in agarose gels, with fiber diameters increasing at higher concentrations and cul-de-sacs appearing at lower concentrations. |
173 Citations | The maze-like structure of agarose gel is formed by the pores, whose diameter and distribution are influenced by both the agarose concentration and the ionic strength of the solvent. |
33 Citations | The agarose gel obtains a maze-like structure due to the formation of fractal aggregates with dimensions near 3, leading to spatial ordering and depletion zones during gelation. |
5 Citations | The agarose gel's maze-like structure is created by non-destructive microneedle photothermal microfabrication, allowing for stepwise formation of microchannels to guide neurites during neuronal network cultivation. |
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