What is ALS healthcare?
Answers from top 10 papers
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| Papers (10) | Insight |
|---|---|
46 Citations | Telemedicine is an effective platform for delivering high quality tertiary ALS care. |
51 Citations | This information provides a foundation for improving ALS care. |
264 Citations | Moreover, accumulating evidence suggests that ALS is possibly a systemic disease. |
Open access•Journal Article | Because ALS is a complex disease, care of ALS patients is best provided at multidisciplinary clinics that specialize in managing patients with this disorder. |
16 Citations | In conclusion, the main problems perceived by patients indicate that increasing awareness of ALS and promoting a proactive attitude among ALS care professionals towards the application for ADHA may contribute positively to the quality of ALS care. |
| In conclusion, ALS teams can consider implementation of valued aspects of case management (accessibility, ample time, proactive approach, emotional support) in the usual multidisciplinary ALS care. | |
40 Citations | It can be concluded that physical and occupational therapy intervention is beneficial to persons with ALS. |
Open access•Journal Article 17 Citations | Cooperation within the healthcare community, among clinicians, patient advocacy groups, pharmaceutical companies, and managed care payers, must occur to advance ALS management and treatment and improve patient access. |
12 Nov 2018 24 Citations | Physical therapy is perceived as an important treatment method by patients with ALS. |
28 Citations | ALS-care supplemented by home-monitoring and nurse practitioner follow-up was shown to be suitable and widely accepted by patients and healthcare professionals in our ALS clinic. |
Related Questions
How does als impact speech?5 answersAmyotrophic lateral sclerosis (ALS) impacts speech by causing neurodegeneration, resulting in decreased speech sound accuracy and intelligibility. The decline in phonemic production accuracy is nonlinear and certain distinctive features, particularly those involving precise lingual and labial constriction and movement, are more important for intelligibility and are more impacted over time. Consonants are more strongly associated with intelligibility than vowels, but both decline over time. ALS patients with respiratory impairment and a restrictive pattern show a negative influence on speech function, with lung volumes significantly correlated to speech impairment. In late-stage ALS, speakers display longer voicing lead and greater occurrence of voicing lead, indicating a disruption in the coordination between supralaryngeal structures and the phonatory system. ALS also affects the functionality of the tongue muscles involved in speech production, leading to changes in tongue volume and contraction patterns during speech.
Amyotrophic lateral sclerosis treatment4 answersTreatment options for amyotrophic lateral sclerosis (ALS) include riluzole, edaravone, sodium phenylbutyrate and taurursodiol (PB/TURSO), and tofersen. Riluzole has been shown to provide clinical benefits such as longer survival time and reduced risk of disease progression. Symptomatic treatments are also used to address common symptoms of ALS, including anxiety, depression, fatigue, muscle cramps, and spasticity. There are several investigational drugs and biological-based therapies currently undergoing clinical trials for the treatment of ALS, with a focus on proteostasis and recovery of functional TDP-43 homeostasis. Impaired insulin signaling and excessive insulin-independent glucose uptake have been found in ALS patients, and insulin-based treatment has shown to be beneficial and disease-modifying. Routine testing for insulin function and treatment if positive results are found is recommended for ALS patients.
Amyotrophic lateral sclerosis (ALS)4 answersAmyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects the motor neurons in the central nervous system. The cause of ALS is largely unknown, with only 2% of cases being attributed to specific genetic mutations. The diagnosis of ALS is primarily clinical, with electrodiagnostic support, neuroimaging studies, and laboratory evaluation used to rule out alternative diagnoses. Multidisciplinary care is recommended for the management of ALS, as it has been shown to prolong survival and improve quality of life. Riluzole is the only approved disease-modifying therapy, but there are numerous symptomatic therapies under investigation. There are overlaps between ALS and frontotemporal dementia, and genetic causes have been identified in up to 15% of ALS patients. Currently, multidisciplinary care and symptomatic management are the mainstays of ALS treatment, with potential for precision medicine approaches in the future.
What is Amyotrophic Lateral sclerosis?5 answersAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that primarily affects the motor system, leading to progressive muscle weakness and wasting. It is characterized by the loss of upper and lower motor neurons in the motor cortex, brain stem nuclei, and anterior horn of the spinal cord. ALS can have extra-motor manifestations, such as changes in behavior, executive dysfunction, and language problems. It can also be associated with frontotemporal dementia (FTD) in some cases. The causes of ALS are heterogeneous and not fully understood, but more than 20 genes have been associated with the disease. The most common genetic cause is a hexanucleotide repeat expansion in the C9orf72 gene. Currently, there is no cure for ALS, and treatment focuses on multidisciplinary care, including nutritional and respiratory support, and symptom management.
What is healthcare?3 answersHealthcare is the improvement of health through the prevention, diagnosis, treatment, and cure of diseases and impairments in individuals. It encompasses physical, mental, and social well-being, and is influenced by genetics, environment, and individual characteristics and behaviors. Healthcare is a broad notion that can be viewed as a service industry with measurable systems, as well as a range of human relational experiences. It is necessary to maintain the body without diseases, illness, or injuries, and may vary depending on cultural, political, and organizational aspects. The healthcare system consists of people, institutions, and resources that deliver health care services to meet the health needs of target populations. It includes efforts to promote, restore, or maintain health, and utilizes health information and communication technologies for evidence-based policy and management.
What is the ALS1 gene IN human?3 answersThe ALS1 gene in humans is the superoxide dismutase type 1 (SOD1) gene. It is the first responsible gene mapped in amyotrophic lateral sclerosis type 1 (ALS1) and codes for the enzyme SOD1, which protects against damage caused by free radicals derived from oxygen. Point mutations in the SOD1 gene are the most frequent in ALS1, with the most common mutations in familial cases being p.A4V, p.I113Y, p.G37R, p.D90A, and p.E100G. These mutations account for more than 80% of cases, although intronic mutations have also been described as responsible for ALS1. Sporadic cases of ALS1 are explained by mutations in other genes such as SETX and C9orf72. ALS1 is a complex disease with genetic heterogeneity, and oxidative stress and ischemia are not the only causes. Clinical studies have shown an increase in cytokines such as adipsin in cerebrospinal fluid.