Why L1 is important in L2 classroom?5 answersL1, the first language, holds significance in L2 classrooms for various reasons. Research indicates that incorporating L1 into L2 sessions can aid language learning by facilitating better understanding, mastering grammar, and expressing complex ideas naturally. Furthermore, L1 can serve as a tool for acquiring new vocabulary, comparing grammatical rules, and forming connections between languages, enhancing cognitive processes in language acquisition. Teachers and students generally favor L1 use in L2 classrooms, especially for specific contexts or goals, supporting the effectiveness of a bilingual or co-taught approach. Additionally, L1 plays facilitating roles in class and task management, scaffolding target language production, and providing conceptual clarification, as seen in pedagogical approaches like CLIL and Translanguaging.
What is the function and role of F2RL1in human cell?4 answersF2RL1, also known as coagulation factor II thrombin receptor-like 1, plays a crucial role in various cellular processes. It has been shown to affect major pathways involved in cell differentiation, adhesion, and proliferation. F2RL1 is abundant in retinal ganglion cells and is associated with new blood vessel formation during retinal development and in ischemic retinopathy. In myocardial infarction, F2RL1 is regulated by the upstream regulatory miRNA and lncRNA, and its downregulation has been found to ameliorate the condition. F2RL1 is also a receptor for F2L, a highly conserved acetylated peptide, and its activation has been shown to have chemoattractant effects on human monocytes and dendritic cells. The function and role of F2RL1 in human cells include its involvement in cell signaling, angiogenesis, and disease progression, making it a potential target for therapeutic interventions.
What is the Thy1.2 gene?3 answersThe Thy1.2 gene is a gene found in mice that codes for the Thy-1.2 allotypic form of the Thy-1 glycoprotein. It has been cloned and its complete exon/intron structure and nucleotide sequence have been determined. The gene consists of four exons and three intervening sequences, and its transcriptional unit produces a tissue and developmental stage-specific mRNA of 1850 bp. The 5' end of the gene has multiple initiation sites and a non-TATA box promoter, while the 3' end has a single polyadenylation site after a long untranslated region. In contrast to mice, humans have only one allotypic form of Thy-1, which is coded for by a gene located on chromosome 11.
How does L1 (first language) affect the acquisition of L2 (second language)?5 answersL1 (first language) has a significant impact on the acquisition of L2 (second language). Bilingual language models (LMs) trained with L1 pretraining showed accelerated linguistic generalization in L2, indicating the influence of L1 on L2 acquisition. In primary schools in China, using L1 to learn L2 has been found to have benefits in language learning, supporting the validity of this learning mode. The errors made by junior high school students in their English compositions reveal the influence of L1 thinking on their L2 acquisition, emphasizing the importance of cultivating second language thinking in junior high school. Incorporating a principled approach to the use of L1 in L2 classroom instruction has been shown to have an effect on L2 acquisition. The role of L1 in L2 acquisition has been a central issue in applied linguistics, second language acquisition, and language learning, with varying perspectives and theories on language transfer.
What are the differences between type 1 and type 2 diabetes?5 answersType 1 diabetes is a chronic disease where the body cannot produce insulin on its own, often diagnosed in younger individuals. It is caused by genetics and immune system destruction of beta cells, leading to absolute insulin insufficiency. Type 2 diabetes, on the other hand, typically affects adults and is characterized by insulin resistance, where the body does not effectively use insulin. It is more prevalent in adults due to an insufficient supply of insulin. Type 1 diabetes is more prone to microvascular complications, while type 2 diabetes is more likely to progress to macrovascular complications. Both types of diabetes have similar emotional reactions and perceive their diagnosis as a major life event. However, individuals with type 2 diabetes express worry for long-term complications, while those with type 1 diabetes describe their diagnosis as a surprise.
What 1 1?5 answersOne is a metaphysical concept that is fundamental to our understanding of the world. It is the notion of being a single entity and is essential for communication, thought, and cognition. The concept of one has implications in various areas of philosophy, including metaphysics, philosophy of language, philosophy of mind, and ethics. There are different senses of oneness, each giving rise to a problem known as the problem of the one and the many. These problems include understanding numerical unity, the relationship between parts and unity, the location of universals in multiple things, and the claim that all things are one. The concept of oneness is complex and has far-reaching implications in philosophy.