scispace - formally typeset
Search or ask a question

Answers from top 7 papers

More filters
Papers (7)Insight
Low antibody avidity may contribute to low index values once infection is established.
In hospitalized patients, clinicians should consider low lymphocyte count as well as the serum levels of CRP, D-dimers, ferritin and IL-6 which may be used in risk stratification to predict severe and fatal COVID-19.
Authors' conclusions The sensitivity of antibody tests is too low in the first week since symptom onset to have a primary role for the diagnosis of COVID‐19, but they may still have a role complementing other testing in individuals presenting later, when RT‐PCR tests are negative, or are not done.
Most COVID-19 patients already have high neutralizing antibody titers at hospital admission.
The findings suggest that low titres of antibody are widespread in the population.
Estimated sensitivities were low, highlighting the limited value of antibody detection in CoVID-19.
Sensitivity has mainly been evaluated in hospitalised patients, so it is unclear whether the tests are able to detect lower antibody levels likely seen with milder and asymptomatic COVID‐19 disease.