What is human redulatory hesperidin intake?
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Human regulatory hesperidin intake is not explicitly mentioned in the abstracts provided. However, the abstracts do discuss the effects of hesperidin on various conditions. One study found that hesperidin supplementation had a significant lowering effect on inflammatory markers such as CRP, IL-6, and IL-4 levels . Another study showed that hesperidin inhibited inflammatory responses in IL-1β-stimulated human chondrocytes, potentially through inhibiting the activation of the NF-κB signaling pathway . Additionally, hesperidin was found to have anti-obesity effects by regulating lipid and glucose metabolism, mediating AMPK and PPAR signaling pathways, and regulating inflammation . These findings suggest that hesperidin may have regulatory effects on various physiological processes, including inflammation and metabolism. However, further research is needed to determine the specific regulatory mechanisms and optimal intake levels of hesperidin in humans.
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