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What is the current view on cryo-TEM? 


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Cryo-TEM is a rapidly advancing technique that is being adopted and applied by materials scientists. It allows for the direct imaging of samples in their native state by rapidly freezing them in amorphous ice and imaging them using a cryo-TEM . Cryo-TEM has been predominantly used for static imaging, but recent advancements in technology have expanded its application to include in-situ experiments in the fields of chemical, physical, and materials sciences . Cryo-TEM is particularly useful for the characterization of materials for quantum information sciences and clean energy technologies, such as exotic electronic states in strongly correlated systems and electron radiation sensitive materials in batteries and solar cells . Cryo-EM, a related technique, is also being used to determine high-resolution structures of proteins and protein complexes, as well as for in situ studies of cellular superstructures . To fully exploit the capabilities of cryo-TEM, it is important to understand the design and functioning of cryo holders and to strategize experiments accordingly . Tagging is becoming a critical technique for cryo-EM to identify biological molecules of interest in the structural studies of cells .

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The paper discusses the recent developments and advances in cryo-electron microscopy (cryo-EM) sample preparation, data collection, and image processing. It does not provide a specific current view on cryo-EM.
The current view on cryo-TEM is that it has gained renewed interest in recent years for its applications in structural biology, quantum materials, and energy-related research.
The current view on cryo-TEM is that it is being adopted and applied by materials scientists, but improvements are still needed to make the technique more accessible and successful.
The current view on cryo-TEM is that it has been predominantly used for static imaging and has expanded its application field due to advancements in technology.

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