What is the effect of dietary selenium on thyroid function?
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Dietary selenium intake has been found to have an effect on thyroid function. Studies have shown that increased selenium intake is negatively correlated with total thyroxine (TT4) and the ratio of TT4 to total triiodothyronine (TT3) in U.S. adults . This association is more pronounced in males and iodine sufficiency adults . Selenium deficiency has been linked to an increased prevalence of thyroid diseases, while selenium supplementation has shown benefits in patients with Graves' orbitopathy and Hashimoto's thyroiditis . Selenium plays a critical role in thyroid function and is particularly abundant in the thyroid gland . However, the optimal selenium concentration must be achieved while avoiding toxic levels, as selenium has a narrow safety level . Overall, the relationship between dietary selenium intake and thyroid function is complex and further research is needed to fully understand its clinical significance .
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129 Citations | The paper states that low selenium status is linked to an increased risk of autoimmune thyroiditis, Graves disease, and goitre. Selenium supplementation in Graves disease may lead to faster remission of hyperthyroidism and improved quality of life. |
| The paper states that dietary selenium has a positive effect on thyroid function by lowering levels of antithyroglobulin and anti-thyroid peroxidase antibodies, as well as reducing the concentration of Thyroid Stimulating Hormone. | |
27 Citations | The paper discusses the role of selenium in thyroid function but does not specifically mention the effect of dietary selenium on thyroid function. |
| The paper states that selenium supplementation improved thyroid function and quality of life in patients with Hashimoto's thyroiditis, but the current evidence does not support the use of selenium supplementation as a routine treatment for thyroid diseases. | |
| The paper states that increased dietary selenium intake is negatively correlated with total thyroxine (TT4) and the ratio of TT4 to total triiodothyronine (TT3) in U.S. adults. |
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